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… provides the scientific community at large with access to high-throughput sequencing and other resources at the JGI for … genome engineering (CRAGE), which offers single-step genomic integration and prototyping of complex …

DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … but in subtle ways that affect fitness. And so, doing a high level kind of analysis, you just might not be able to …

The IMG group owns and maintains integral components of JGI’s production workflow, and is responsible for the … ANI is used to ascertain the species specificity of single cells and genomes extracted from metagenomes, and also as a …

… as user facility that aims to provide access to state-of-the-art DNA synthesis and assembly technologies to the … such as those involving biosynthetic clusters, or high complexity combinatorial libraries.  We have developed … adoption of lab automation enabling ever-higher levels of throughput. We also develop methods for efficient QA/QC …

… for Ocean Sciences described a novel technique to access high-quality genomic information using minute quantities of DNA derived from individual environmental cells. The proof of principle study built off earlier … and finished genome derived from an uncultured bacterial single cell – a symbiont of the green sharpshooter. In 2012, …

… … DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I wanted to tell … come, though, too when you start talking about going after single gene clusters. BRIAN BACHMANN: That’s right. JACKIE … mammalian systems. But it allows us to assay on a single cell level against cell lines and against primary cells …

… mining and the directions it might take in the future. I highly recommend it. I’ll link to it in the show notes. … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all … is not on the data side, but it’s still really the high throughput of getting these clusters activated. So most of …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which are not essential for … (BGCs), advancing pathway analysis, optimization of cell- and cell free-based expression platforms, tools and …

… more economic, they also would like to extract some high– what they term “high value–“ Dan Udwary: Right. Kate … both of those things have still very much done to be excellently. Dan Udwary: For sure. Kate Duncan: Not that … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… group aims at improving our collective understanding of ecological and evolutionary parameters driving virus:host … mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… … DAN: You’re listening to the US. .Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … at, historically, for these pathways, they’ve got really high GC content, which means their base usage is skewed, and … in putting antibiotics together, getting them out of the cell letting them do their dirty work. So that’s one arm. …