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Natural Prodcast Episode 16: Marcy Balunas
… to go with this.  MARCY: Yes. And so we started out in the universe of natural product isolation. And in listening to …
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Natural Prodcast Episode 1: The Primer, Part 1
… After that, we have lots of great conversations that we’ve already recorded with some excellent scientists, and that’s …
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Natural Prodcast Episode 2: The Primer, Part 2
… from fungi, and Taxol from plants. Plants, fungi, bacteria, archaea, they all have secondary metabolism. They all have … to one another – to sort of know if their neighbors had already been to a location or something by leaving sort of a … but bacteria, you’re a little bit more giving. DAN: Alright, so I think we’ve covered a little bit about why …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… uh– ALISON TAKEMURA: I had snow. DAN UDWARY: You had snow already. Yeah, that’s crazy. ALISON TAKEMURA: Yeah. DAN … And what this is, is a data set of bacterial and archaeal genomes that were created – these are Metagenome … we’re going to add another 87,000. So that’s, what, a 20%, 30% increase?  Dan insert: It’s a 21.75% increase. ALISON …
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Plant Microbial Interactions Group
… 10.1038/s41396-020-0637-z 10.1038/s41477-024-01666-3 10.1016/j.celrep.2023.112676 10.1016/j.devcel.2022.01.008 … 10.1038/s42003-021-02477-4 10.1038/s41477-021-00915-z 10.1073/pnas.1907500116 10.1016/j.celrep.2019.04.054 …
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Industry Engagement Program
… by industry. When Director Nigel Mouncey joined the JGI in 2017, he brought with him 20 years of industry experience — …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… systems determine mutualism or parasitism between some archaeal hosts and their hitchhikers. The Science Within the archaeal domain, there is a group of tiny hitchhikers. These … gaps, they must latch onto a larger host — often, a fellow archaeal microbe. Understanding how these hosts and …
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Data Policy
… for which JGI has not yet received samples as of Sep 30, 2021 are subject to a 2-year embargo to maintain the … Data from projects that received samples before Sep 30, 2021 and are ongoing are subject to the 2-year … JGI will no longer produce use-restricted data except in already active projects as described above, but JGI portals …
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Mining Metagenomes for Cas Proteins
… Cas14 proteins discovered from JGI’s IMG/M database and … aa. They were initially identified by searching for Cas12d homologs across IMG/M’s assembled metagenomic data. It … the Cas14 proteins identified were found within the archaeal superphylum DPANN, named by a JGI-led team for the …
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Tracking the Origins of Methane-Producing Microbes
… Mini-Metagenomics Approach Helps Identify Novel Archaeal Methane Metabolism. Methane-producing archaea are … discovered genomes. When they analyzed the reconstructed metabolisms, they found that one of the MAGs contained the …
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Natural Prodcast Episode 9: Roger Linington
… like to build would greatly benefit by knowing what’s already known. So you can imagine, if you have a particular … from ground zero again in order to solve what might be an already known compound. ROGER:  However, if you had a … about the topic we cared about. And that gave us about 12,000 molecules. And that was enough for us to build a …
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Natural Prodcast Episode 17: Cassandra Quave
… it and enjoy it and learn a ton. And for those of us who already work in natural products, you’re going to get a great … and killing plants, so if you haven’t figured that out already from the book, not so great at growing them, … convention went– since the protocol went into force in 2014. There’s now a website that has a lot of resources that …
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