Search

… in. All proposals must be written in English. … The CSP and FICUS calls are open to both domestic and … Agreement must be signed before work can begin, and all CSP proposals are subject to JGI policies on Data Release and Publication .   Except for applicants to the CSP New Investigator call, investigators may have existing …

Genomics group . Research Team … Coclet, C. and Roux, S. (2021) Global overview and major challenges of host … Opinion in Virology .  49 , 117-126 Berg, M. and Roux, S. (2021) Extreme dimensions — how big (or small) can tailed … Nature Reviews Microbiology.   19 , 407 Berg, M. et al. (2021) Host population diversity as a driver of viral …

… always been the main driver for secondary metabolism drug discovery. Because we always need new antibiotics. We need … doi: 10.1038/s41587-020-0718-6) The GEM catalog expands the bacterial and archaeal orders as seen on the phylogenetic … but in subtle ways that affect fitness. And so, doing a high level kind of analysis, you just might not be able to …

… the modern, post-golden age history of natural products discovery, and we’ll talk a lot about the current state of … sparked your interest, and you want to learn more, then I highly recommend David Hopwood’s book called  “Streptomyces … in Nature and Medicine.” It’s obviously focused more on the bacterial side of the field, and it’s a little hard to find …

… been dominated for … well, as long as I can remember, by bacterial research.  So it was great to hear her passion and … was there for about three and a half years – I worked at a high school. And one of the things that I noticed is all the … I wish we could predict. I wish we could look at these enzymes and predict, and really place it to structure. …

… at the JGI; and overview of the Community Science Program (CSP). A crucial job of the committee is to take the input from the CSP Proposal Study Panel on prioritization of CSP projects and, with concurrence from the DOE Office of …

Program leads to discuss available options. Note: In 2021, we conducted an extensive internal product audit to … ( IMG ) 280/298 Microbial Improved Draft, Isolate High quality draft assembly of long-read sequence data, … times, so please ensure your DNA/RNA sample quality is as high as possible to minimize failure. …

… least a certain level of similarity. So if similarity was higher than a certain kind of volume. And if you do that, … Integrated Microbial Genomics at JGI, a large data set of bacterial genomes. And so yeah, we use antiSMASH to identify … relates to a whole different field like computational drug discovery field, which has been quite distinct from the …

… and should generally conform to the guidelines for our  CSP Large Scale call .  Process Proposals may be submitted … will develop fuels and products by integrating three highly interconnected DOE priority areas of Feedstock … advanced biofuels. The center focuses on creating robust high-yielding feedstock plants, using advanced genetic …

… through the stories I told you about geosmin, which is a bacterial sacred metabolite, and ergot alkaloids come from … metabolism, has been … not dominated by, but driven by drug discovery. We know that many natural product molecules are … that do things for us that are positive. And so drug discovery has been a major driver for natural product …

… that will open up a new year for targeted anti cancer drug discovery. DAN: Yeah, great. Are any of these antibody-drug … this collection in total contains approximately 100,000 bacterial strains, and a hundred thousand fungal strains. … why the stereochemistry was that way. And he told me, it’s enzymes. It’s magic.  BEN:  Yeah, right.  DAN: I thought …