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… Professor Eric Schmidt, from the University of Utah. I’ve known Eric for a long time – we worked together on Aflatoxin … high altitude! And a lot of us moved on to work in simpler systems, like bacteria, where we figure we can make more … It was in pieces. And so one of the things that’s really advanced us over the last few years is, everyone in the …
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… yes, sure, right. And yeah, so we worked on the Salinospora genomes. That was a really fun project. We had Brad on and … obligate marine. There’s so far no species or no strains known that really grow in freshwater. But they’re actually … protein or the genes that you are analyzing. And then we’re building phylogenies a lot, making phylogenetic trees, and …
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… Biology is currently experiencing a revolution brought on by … data, coupled with recent computational technology advances in management, processing and visualization of “big … discoveries and catalyzing a major transition of biology into data science. Research in the Kyrpides group …
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… called Cochliobulis heterostrophis . This is a very well known fungus because it produces a secondary metabolite or … DAN: Got it. NANCY: And this is really to complete the genomes, and I’m really thankful for this. It sort of goes … now to understand that a little bit better, with some advances in evolution and cell biology. I’m interested in …
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… now we really want to explore some of the ones that are unknown. And so we've done the sequence similallity network … in is actually seeing whether we could go into the genomes and predict what the natural product might actually … does a beautiful job of marrying synthetic chemistry, building these products that then you can then apply …
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… it’s something that we have. There are animals that are known to be sources of secondary metabolites, like sponges … and you can see that different Frankia have different size genomes depending on what kinds of plants, and what kinds of … metabolites. And they often use primary metabolites as building blocks to produce novel molecules. And so we’ve got …
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… and viruses. Listen in to explore the data that illuminates biology, and hear how it could power our future. …
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… Institution of Oceanography. And Brad and I, Alison, have known each other for quite a while because Brad was my … all those art history photos of the, you know, various old buildings in in Rome didn’t quite do it for me. And at the … Sequencing Program, and they worked with us to sequence two genomes. Those were of Salinospora tropica and arenicola . …
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… of publications and allowing connections between all systems to maximize the impact of user research. The crucial …
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… Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic data, open to all researchers. … analysis and annotation of all publicly available genomes from three domains of life, in a uniquely integrated … metagenome sequence, in the context of reference isolate genomes included from the IMG/M system. …
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… “We’ve more than doubled the number of protein families known up until now, and identified many novel structure … through the publicly available Integrated Microbial Genomes & Microbiomes (IMG/M) database, they successfully … environment — whether that be soil, animal hosts, marine ecosystems, etc. “So, they must be doing something interesting …
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