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2024 Progress Report
… for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … A record number of primary users — 2,456 — had active proposals with us, … We generated 871 Terabases of sequence We synthesized 9.7 Megabases of DNA We processed 13,700 metabolomics samples …
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Engagement Webinar: What Can You Do With An Approved CSP Functional Genomics Call Proposal?
… call is open year-round, but proposals submitted by July 30 will be included in the next review. “So webinars like … really fully exist back then,” said Hal Alper, a University of Texas at Austin professor, “but we really first heard … the request size, being permitted to request up to 1.5 megabases (MB) of a synthesis, compared to 0.5 MB for a …
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Fungus Fuels Tree Growth
… start pinning down how a fungal symbiont spurs growth of poplar, a potential biofuel feedstock.     The Science The fungus  Mortierella … and without an inoculation of the  M. elongata strain PM193 added to a diluted soil mixture, publishing  the results … the Oak Ridge National Laboratory (ORNL) sponsored by the Office of Biological and Environmental Research at the …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most species do not grow easily in the … that were acquired through it were usually only around 30% complete.  Described in  ISME Communications , a method …
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JGI at the AGU Fall Meeting
… Register for the meeting here. Here are some sessions of interest (all times in PST unless otherwise noted): … December 7   9:15am PT (online) Town Hall on the role of user facilities in accelerating research and tips for … User Facilities in One Proposal via FICUS December 13 8:12 am Convention Center eLightning Theater IV: Kuno …
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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory protein. Researchers demonstrated … 18, with the number of factor-gene pairs almost doubling to 399. Two of the 11 sigma factors addressed in the study were …
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First Monoploid Reference Sequence of Sugarcane
… . The Science Most species are diploids and have two sets of chromosomes, one from each parent. In contrast, many crops have multiple sets of chromosomes (they are “polyploid”) and their complex … as a reference. The final sugarcane sequence generated is 382 Mb; 25,316 protein-coding gene models were predicted …
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Extracting the Secrets of Secondary Metabolites
… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … effectiveness has historically been limited due to the lack of robust tools available for carrying CRISPR into … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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Virus Discoveries that Keep Getting Bigger
… single-cell work — have quickly accelerated understanding of giant viruses. The Science In the last thirty years, in … genomes than many bacteria. Until recently, understanding of giant viruses came primarily from sampling an … approaches to gain insight into the  genomes of giant viruses. In a new review, researchers from the U.S. …
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Graduate Students Get Thesis Research Opportunity at the JGI
… Twice a year, the DOE Office of Science Graduate Student Research (SCGSR) program awards … at 12 host national laboratories or facilities between 3-12 consecutive months. Their proposed research projects … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Applying Viral Genomics Expertise to Understanding the Human Virome
… viruses outnumber the microbes by at least another order of magnitude. For years, scientists at the DOE Joint Genome Institute, a DOE Office of Science user facility located at Lawrence Berkeley … The work is supported by NIH Common Fund grant 1U01DE034196-01. The JGI team, including Kyrpides, Camargo, and …
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Triggering Morel Fruiting
… A collaborative team led by Hao Tan from the Sichuan Academy of Agricultural Sciences in China and involving Francis … in France and Igor Grigoriev from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … China, and a wild black morel strain M. importuna CCBAS932 from the forests of France, were sequenced and annotated …
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