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… for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … in our new Strategic Plan , which was released in April 2024 — through serving an increased number of users with a … We generated 871 Terabases of sequence We synthesized 9.7 Megabases of DNA We processed 13,700 metabolomics samples …

… really fully exist back then,” said Hal Alper, a University of Texas at Austin professor, “but we really first heard … [DNA Synthesis Science Head] Yasuo [Yoshikuni] gave back in 2016.” Alper’s first approved JGI proposal came through the … the request size, being permitted to request up to 1.5 megabases (MB) of a synthesis, compared to 0.5 MB for a …

… start pinning down how a fungal symbiont spurs growth of poplar, a potential biofuel feedstock.     The Science The fungus  Mortierella … it can thrive in the soil as a saprophyte, living off decaying organic matter, or as an endophyte, living … the Oak Ridge National Laboratory (ORNL) sponsored by the Office of Biological and Environmental Research at the …

… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most species do not grow easily in the … like plasmids, the picture is far from complete.  In 2021 , scientists at St. Jude Children’s Research Hospital …

… Register for the meeting here. Here are some sessions of interest (all times in PST unless otherwise noted): … December 7   9:15am PT (online) Town Hall on the role of user facilities in accelerating research and tips for … User Facilities in One Proposal via FICUS December 13 8:12 am Convention Center eLightning Theater IV: Kuno Kasak, …

… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory protein. Researchers demonstrated … efficacy of RIViT-seq, researchers recently characterized 12 sigma factors and were able to identify the associated …

… . The Science Most species are diploids and have two sets of chromosomes, one from each parent. In contrast, many crops have multiple sets of chromosomes (they are “polyploid”) and their complex … as a reference. The final sugarcane sequence generated is 382 Mb; 25,316 protein-coding gene models were predicted with …

… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … in overcoming this obstacle when it hit the scene in 2019. Now, that power is poised to grow exponentially by … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …

… single-cell work — have quickly accelerated understanding of giant viruses. The Science In the last thirty years, in … genomes than many bacteria. Until recently, understanding of giant viruses came primarily from sampling an … virions (700 nm in diameter) to much smaller virions (120 nm in diameter). Across the phylum  Nucleocytoviricota , …

… Twice a year, the DOE Office of Science Graduate Student Research (SCGSR) program awards … of the latest call , a total of 70 graduate students from 52 universities were selected to carry out part of their … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …

… viruses outnumber the microbes by at least another order of magnitude. For years, scientists at the DOE Joint Genome Institute, a DOE Office of Science user facility located at Lawrence Berkeley … metagenome-assembled viral genomes ( Nature Biotechnology , 2021), geNomad , a tool for identifying mobile genetic …

… A collaborative team led by Hao Tan from the Sichuan Academy of Agricultural Sciences in China and involving Francis … in France and Igor Grigoriev from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … assimilated carbon into the soil, reducing the amount of CO2 emissions from decaying leaves and woods into the …