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Taking Stock of the Known and Unknown Microbial Space
… global research community.  Published January 17, 2025 in Science Advances , researchers at the U.S. Department of … data are publicly available in the National Center for Biotechnology Information (NCBI) GenBank collection and on the … representation. “When it comes to isolate genome data, our real-world touchstones, we’re just scratching the …
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2023 Progress Report
Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … complex biological and environmental systems. We optimize our service to the community through responsibly managing our people and resources.   Director's Perspective   Honors …
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Busting the Unbreakable Lignin
… fungi can degrade the hardiest of plant components   The Science There are three main ingredients to tackle when it … yield fuels, and removing lignin in order to do so is a resource-intensive process. Now, a new study shows how … component, lignin, that has historically been less of a resource to be extracted and more of an obstacle to breaking …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
Tel Aviv University in Israel, the National Center for Biotechnology Information, and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … system. “We then looked into many more samples and refined our methodology,” Neri said. “Our team grew and so did the …
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Evolution of a Fungal Gene Expression Regulator
… date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or G in a genome sequence can … no. DE-AC02-05CH11231. The Georgia Advanced Computing Resource Center (GACRC) and Georgia Genomics and Bioinformatics … of Georgia provided sequencing and computational resources, respectively. This work was supported by the Office …
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Extracting the Secrets of Secondary Metabolites
… helps further demystify biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not … make up the foundation for a slew of vital products in biotechnology, medicine, agriculture, and other industries — … Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National …
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JGI Announces 2025 New Investigator Portfolio
Yaqi You, Yong Zhang and Zhiping Zhong. (All images courtesy of the researchers) Each year, the JGI searches for … accepted proposals.  The New Investigator call , part of our  Community Science Program , allows us to work and share our tools with …
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Tracking the Origins of Methane-Producing Microbes
… published in the Proceedings of the National Academy of Sciences , researchers at Stanford University, the Chan … These two things combined led us to conclude that our new methanogen did not belong to the Euryarchaeota, the … working to address some of the most pressing challenges of our time. For more information, please visit  …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… of peat moss drives insight into carbon storage   The Science Boggy peatlands, which hold much of the Earth’s … as carbon sinks and minimize their role as carbon sources. Summary Sphagnum, a genus of just under 400 mosses … National Laboratory, and the HudsonAlpha Institute for Biotechnology sequenced sphagnum  genomes from plants selected …
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The Power of One, Amplified
… single cell genomics complements metagenomics studies. The Science Researchers demonstrated the value of conducting … potentially of use in fields ranging from agriculture to biotechnology and medicine, the vast majority in, on, and … microbial populations. The work appeared in The ISME Journal . Members of the Dunfield lab collected samples from …
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Supercharging SIP in the Fungal Hyphosphere
… helps ID novel interactions between bacteria and fungi The Science Researchers have successfully automated aspects of a … with potential applications in industry and biotechnology for the production of  clean energy . Summary … of Energy Joint Genome Institute, a DOE Office of Science User Facility at Lawrence Berkeley National …
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2022 Progress Report
Microbiome Data Collaborative (NMDC), and Berkeley Lab Biosciences Area are also co-located in the IGB. Vision The … Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user facility at Lawrence Berkeley National … (Berkeley Lab), is to become the leading integrative genome science user facility enabling researchers to solve the …
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