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JGI Workshop at SIMB NP Meeting
… untapped metabolic capabilities is often tedious and resource intensive. This is often due to, for example, tight regulation of biosynthetic gene clusters … needed to predict BGCs from available genome sequences. The DOE Joint Genome Institute (JGI), a DOE Office of Science …
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Researching and Solving Real-World Problems with the 2023 JGI-UC Merced Interns
For the first time in several years, the DOE Joint Genome … And we’ve been working on isolating and cultivating and sequencing extremophile protists from a hypersaline alkaline … skills, wet lab skills and overall connections. Theo Loureaux : I wanted to first discover new methods with tools …
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Boosting Small Molecule Production in Super “Soup”
… to make products such as proteins, and the mechanisms for maintenance to keep processes running smoothly. As … able to make the same amount of a product in just eight hours that growing cells take three days to make, which is a … and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that enable …
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Identifying the Microbial Cleanup Crew at a Superfund Site
… the microbial community involved in a bioremediation effort. The Science In 1999, the Environmental Protection … down PCE into the chemical compound ethene. Applying genome sequencing and analysis, the researchers identified other … populations rely heavily on groundwater as their only source of clean drinking water. Over 90% of the PCE in the …
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Sequencing crop genomes: approaches and applications
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Selection to sequence: opportunities in fungal genomics
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Frameshift detection in prokaryotic genomic sequences.
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Draft Genome Sequences of Switchgrass Diazotrophs
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Gene Expression: From On-Off Switch to Dial
… approach to expression, scientists can now opt for various shades of grey. The ability to fine-tune the … and included researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science … Camille and Henry Dreyfus Foundation, and the JGI Synthesis Program under FP00005685. In addition, M.D. acknowledges …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… such as heat waves, droughts and floods. The planet’s resources are being stretched by a growing human population and increasing demand for agricultural products.  Sorghum bicolor (L.) Moench is … nearly 400 root and leaf samples and helped analyze the sequencing datasets. The results from the first year showed …
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Green Algae Reveal One mRNA Encodes Many Proteins
… zofingiensis . “I was scrutinizing the genes of one of our species of algae and kept seeing what looked like … research team included scientists at the University of California (UC), Berkeley, UCLA, UC Davis, Brookhaven National … and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that enable …
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Danielle Goudeau
Danielle operates the single-cell genomics pipeline for JGI collaborators. This work combines … cell sorting, genome amplification, PCR screening, and 16S sequencing. She also develops novel flow cytometry protocols …
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