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Applying Promiscuous RiPP Enzymes to Peptide Backbone N‑Methylation Chemistry
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A Community Resource for Secondary Metabolite Researchers
… shared by most living creatures for energy, growth and reproduction—most organisms produce a set of "secondary metabolites," chemical … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence …
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A Collaboration to Improve Plant Genome Annotations Across Species
… To provide broad plant genomic capabilities, the DOE Joint Genome Institute works … which specializes in genome improvement for plants. As part of that partnership, the JGI and HudsonAlpha …
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JGI@25: From Life at the Extremes to Editing Genomes
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … led by Nikos Kyrpides , mining the Integrated Microbial Genomics & Microbiomes (IMG/M) system’s immense collection … nature was using it to do something important.” Related Publications:  A scoutRNA Is Required for Some Type V …
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Corymbia Genome Expands Terpene Synthesis Knowledge
… Genome annotations of two C. citriodora subspecies broaden understanding of the terpene synthase gene family across eucalypt … desirable from a biofuels production perspective. By using genomic database alignment tools, researchers searched for … This work was supported by the Australian Research Council (grant numbers DP140102552, …
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From Competition to Cooperation
… genomes, researchers were able to carry out a broader analysis than had ever been done before to look at how multiple forest … will assist researchers in moving toward functional genomics studies to learn more about the inner workings of … Genome Institute, a DOE Office of Science User Facility, and supported by the Office of Science of the U.S. …
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An Automated Tool for Assessing Virus Data Quality
… CheckV can help researchers assess virus sequence fragments and data … the blind men who encounter an elephant for the first time. Based on the single body part each blind man touches – a … well as sequences from the Global Ocean Virome 2.0 dataset based on open ocean samples. CheckV identified a total of …
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Graduate Students Get Thesis Research Opportunity at the JGI
… is Mo Kaze, part of the 2018 cohort of the JGI-UC Merced Genomics Internship Program. Kaze is part of Mark Sistrom’s … of Natural Sciences. “I’m deeply concerned about climate change and this is a remarkable opportunity to launch a pilot … a variety of disciplines who seek to better understand the ecological importance of virus-microbe interactions,” Rambo …
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
… for the first time. For years, Elizabeth (Toby) Kellogg and other researchers at the Danforth Plant Science Center (Danforth Center) drove up and down the … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …
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Uncovering Novel Genomes from Earth’s Microbiomes
… Large-scale comparative analysis leads to identification of biosynthetic gene … secondary metabolites for multiple applications. Despite advances in sequencing technologies and computational methods … and the  DOE Systems Biology Knowledgebase (KBase) . Metagenomics is the study of the microbial communities in the …
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Rational Reprogramming of O‑Methylation Regioselectivity for Combinatorial Biosynthetic Tailoring of Benzenediol Lactone Scaffolds
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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
… Streamlined genome with precise gene targeting transforms oil-producing alga into a powerful platform for developing ​​bio-based industrial products.    The Science Scientists have … relationships than other algae, Auxenochlorella ’s reduced genomic complexity can accelerate the design-build-test …
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