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Plant Microbial Interactions Group
… Selected Publications …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… data, a new JGI tool more accurately facilitates microbial genome discoveries. Unlocking the intricate details of … the data it is trained on,” Wang said. “Most models rely on reference genomes to train genome foundation models. … on efficiency and diversity in sampling is to help avoid common pitfalls that similar models have historically …
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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
… Streamlined genome with precise gene targeting transforms oil-producing … products.    The Science Scientists have fully decoded the genome of an oil-producing green alga, and demonstrated precise gene targeting in the genome in the November 2025 issue of The Plant Cell. …
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Engagement Webinar: What Can You Do With An Approved CSP Functional Genomics Call Proposal?
… of terpenoids, naturally occurring organic chemicals with a wide range of potential applications. Q&A from the Webinar … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility … integrated high-throughput sequencing and computational analysis that enable systems-based scientific approaches to …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… are abundant and yet exceptionally small, with mini genomes to match. As a result, they cannot process all of … coexist is key for understanding their impact on wider ecosystems, but these symbiotic interactions are … they analyzed both host and hitchhiker genomes for commonalities. In host genomes, they found a huge variety of …
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Leo Baumgart
… Dr. Baumgart joined the DOE Joint Genome Institute in 2018, following his doctoral research in … factor binding sites and which has been applied to a wide range of JGI user science projects spanning bacteria, … to characterize gene regulation at the level of individual cells across diverse plant tissues. Dr. Baumgart …
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Expanding Virophage Diversity
… Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant … Almost all known virophage genomes share only four genes in common: major and minor capsid proteins (MCP and mCP, … including over 28,000 unique MCP sequences.  Further analysis led to the identification of 328 “high quality” …
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Evolution of a Fungal Gene Expression Regulator
… in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures … development. Summary With the aim of producing at least one reference genome for every family of fungi, the 1000 Fungal … Additionally, the team found a correlation between genome-wide 5mC abundance and the abundance of specific 5mC …
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Comparative Analysis of 126 Cyanobacterial Genomes Reveals Evidence of Functional Diversity Among Homologs of the Redox-Regulated CP12 Protein    
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IMG-ABC: new features for bacterial secondary metabolism analysis and targeted biosynthetic gene cluster discovery in thousands of microbial genomes
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Identification of candidate genes in Arabidopsis and Populus cell wall biosynthesis using text-mining, co-expression network analysis and comparative genomics
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Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth
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