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Gene Expression: From On-Off Switch to Dial
Scientists have developed a more nuanced library approach to tuning gene expression in metabolic pathways. Compared to the traditional way, which leverages … gene expression on two energy-filled sugars used in biofuel production, glycerol and galactose. Although they are …
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Tracking the Origins of Methane-Producing Microbes
Methane Metabolism. Methane-producing archaea are estimated to produce 500 million tons of methane a year, which is over half the total global methane production. They are thought to use billions of tons of the … carbon cycle. All methanogenic archaea use one of three pathways for methanogenesis: hydrogen-dependent and …
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The Expanding Universe of Methane Metabolisms in Archaea
Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse gas 20 … which form it emerged and how it gave rise to the different pathways we see today is not only important to understand … between Archaea and Eukarya.   One genome, two metabolic pathways “Up to this point, most phylogenomic trees have …
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Jeremy Schmutz
… involvement with the DOE Joint Genome Institute dates back to 1997, when he was working for the Stanford Human Genome … novo sequencing of eukaryotic organisms from simple yeasts to large vertebrate genomes.  For the past 13 years, Mr. … JGI Plant Flagship Genomes and DOE relevant cellulosic feedstocks. Schmutz provides scientific project management for …
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Supercharging SIP in the Fungal Hyphosphere
High-throughput stable isotope probing helps ID novel interactions between bacteria … and fungi The Science Researchers have successfully automated aspects of a commonly-used process for studying … applications in industry and biotechnology for the production of  clean energy . Summary Arbuscular mycorrhizal …
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New Research Finds Flagella in the Terrestrial Roots of Marine Bacteria
… ditched their flagella and other traits when migrating back to the ocean. The Science Scientists have discovered … could help inform engineering microorganisms for biofuel production and other sustainable applications. Summary Hot … . Since these bacteria lack complete biochemical pathways to break down plant material on their own, they …
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The JGI announces 2024 awardees for our Community Science Program annual call
From left to right: [above] Olivia Ahern, Adriana Corales, Hugh Cross, … Tesfaye Mengiste, Egbert Schwartz, Hannah Schulman, Bram Stone and Jana Voriskovaa The JGI is excited to announce the … (BER) missions in: sustainable biofuel and bioproducts production, global carbon and nutrient cycling, and …
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How Filamentous Fungi Sense Food
Tracing gene regulatory networks in the model fungus  Neurospora crassa . The … approach to reconstruct and model gene regulatory pathways used by the filamentous fungus  Neurospora crassa, … for bioenergy researchers looking to improve the industrial production of sustainable biofuels and bioproducts. …
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Nikos Kyrpides
Dr. Kyrpides joined the DOE Joint Genome Institute in 2004 to lead the Genome Biology Program and the development of … Microbial Genomes and Metagenomes Program since 2011. Prior to joining the DOE Joint Genome Institute, Dr. Kyrpides led … A Knowledge-Based Bioinformatics Framework for Microbial Pathway Genomics (MICROME); Metagenomics of the Human …
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Mindfully Moving JGI
… in the process of shifting its operations from Walnut Creek to the heart of the Berkeley Lab campus. By Friday, October 18, the production sequencing labs in Building 100 were silent. …
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JGI Earth Month: Wetlands Work in #TenHundredWords
… and DNA Day on April 25. As both Earth and DNA are close to our JGI hearts, we’re highlighting genomic science research that feels especially relevant to living on a changing planet. Mo Kaze is a University of … project, “Microbial Community Structure and Methane Production in California’s Canal System,” focuses on …
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The JGI announces FY25 awardees for our Community Science Program Annual Call
…   The JGI is excited to announce the 18 scientists selected for our 2025 … Annual Call. These projects include cutting-edge research into microbial communities — from freshwater estuaries … (BER) missions in sustainable biofuel and bioproducts production, global carbon and nutrient cycling, and …
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