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… is for investigators and research initiatives new to the JGI. Projects must be independent of ongoing JGI proposals, and lead PIs cannot have been lead PI on any previously accepted JGI CSP or FICUS proposal.   Competitive projects will … Proposers are encouraged to review the JGI’s sample requirements . Samples that are not available …

… JGI innovates protocol revealing how genetic variations in … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … the amount of time it takes to produce a dataset from months to days and halving the total reagent cost. While …

… uses single-cell genomics and metagenomics to explore how microbes influence people and the environment. This includes … studying the diversity, physiology and community ecology of microbes sampled from the natural environment. …

… changed dramatically over the last  25-plus years since the JGI’s inception, making it possible for researchers to get a … ecosystems and organisms than ever before. In 2006, the JGI produced 33 billion base pairs of sequence; by 2023, … ecologist and JGI user Trina McMahon has been sampling microbes at Lake Mendota, which borders the University of …

… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … Computational Sieves to Filter Sequences There are more microbes on the planet than particles in a handful of dirt, … are even less known than DNA viruses,” said Simon Roux , a JGI scientist and one of the project co-leads. “But same as …

… One of the JGI’s key assets is our user community, comprising a broad range of researchers and trainees who use JGI resources and expertise. These collaborations have … outputs, such as data, publications and software. The JGI supports the entire data life cycle, and embeds metadata …

… Danielle operates the single-cell genomics pipeline for JGI collaborators. This work combines custom flow cytometric … flow cytometry protocols for targeted recovery of specific microbes. …

… The JGI’s Science Programs offer support to users and their research efforts.  JGI scientists lend their expertise to enhance the … for them. Their concerted efforts help maximize the JGI’s impact in advancing both user science and the DOE …

… The JGI has diverse capabilities in: DNA and RNA sequencing, … is provided for all sequencing products below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the … for a proposal, we encourage you to contact the relevant JGI  Science Program leads to discuss available options. …

… how a fundamental mechanism of evolution allows microbes to adapt to changing environments. The Science The … the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user facility located at … data, approximately half of which was generated by the JGI, to uncover these DGRs. DGRs were found in single …

… it. The isotopes are incorporated into the DNA of specific microbes who consume the labeled food or water. Later, their … which microorganisms used the labeled substance and which microbes did not. This is normally an arduous wet lab … HT-SIP is a capability available to request through  the JGI proposal calls . …

… to integrate large genetic payloads directly into diverse microbes. Combining CRAGE with CRISPR provides researchers … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … CRISPR to knock out or activate genes, researchers at the JGI were able to monitor loss- and gain-of-function. The …