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Extracting the Secrets of Secondary Metabolites
… combo helps further demystify biosynthetic gene clusters.  The Science Microbial secondary metabolites, those … paired CRISPR and CRAGE technologies. While CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is … and other industries — yet there’s still so much about them we don’t know.  Unlocking the power of secondary …
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Annual Genomics of Energy & Environment Meeting
Thank you for joining us at the 2024 DOE Joint Genome Institute (JGI) Annual … challenges.  The invited talks emphasize how the research infrastructure – DNA sequencing, synthesis, metabolomics, …
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Gene Expression: From On-Off Switch to Dial
… approach to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of … of essential genes in metabolic networks that were missed using traditional approaches. This novel form of … the realm of bioenergy optimization. Summary Life is all about balance. This study,  recently published in the  …
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Access to Rock Star Scientists
… so nice and helpful.”     Mo Kaze, UC Merced JGI Mentor : Susannah Tringe, Microbial Systems Group “Everyone here is very kind and really open to talking about their work. It’s fun to be around people who are generous with their time and like nerding out about the big stuff, well, the little stuff! People hold …
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Fungus Fuels Tree Growth
… a potential biofuel feedstock.     The Science The fungus  Mortierella elongata enjoys a dual lifestyle; it can … an endophyte, living between a plant’s root cells. The fungus is almost always found among and within poplar trees, and … were striking. Adding PM193 caused poplar cuttings to grow about 30 percent larger by dry weight than without PM193  . …
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Gotta Catch 'Em Gall
… called galls.  In this episode, hear from Kasey and Patrick about how this project unfolded, and how they worked with the JGI's metabolomics program to find out more about these weird little pods. …
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Triggering Morel Fruiting
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility,  reported on just how morel fruiting is triggered when … The JGI provides integrated high-throughput sequencing and computational analysis that enable systems-based scientific …
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Finding the Fermenters
… of fermentative prokaryotes. The Science Most organisms use oxygen to convert food into energy. However, in … or no oxygen, life had found other ways to produce energy, using a process called fermentation. To better understand … used the JGI’s GOLD and IMG data portals to get information about the genomes and genes of the organisms on the list. …
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Alabama A&M Interns Access An Abundance of Knowledge
… fellow interns and scientists alike. Want to learn more about their experience? Watch the short video below. Video … fall for my master’s in plant soil science and my career focus is plant breeding. Ti’Yanna Watson: My mentor is Dr. Yi … through climate change. Ti’Yanna Watson: The best part about interning here is the community aspect. Everyone here …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… they need to survive. To fill in their nutrient gaps, they must latch onto a larger host — often, a fellow archaeal … new views of these relationships.  Recently , researchers used population genomics to find that while archaeal … cycling across the planet. Summary To understand more about how archaeal hosts and hitchhikers coexist, …
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The Case for Conservation
… crop yields.  The Science The fire moss Ceratodon purpureus is a short plant with a complex genome . Now, … Carey, now at the HudsonAlpha Institute for Biotechnology, reported that high quality genome references are now … HudsonAlpha. As the team discussed in a JGI podcast episode about the work, the effort to fully sequence the fire moss …
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How Filamentous Fungi Sense Food
Tracing gene regulatory networks in the model fungus  Neurospora crassa . The Science A team led by researchers at the University of California, Berkeley used a multi-omics approach to reconstruct and model gene … degrade the plant biomass. In order to learn more about these regulatory networks in the model fungus  N. …
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