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JGI@25: Fueling Investigation into Methane-Making Microbes
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … to provide colleagues at the Salk Institute with genomic DNA samples from Ruminococcus flavefaciens (XPD3002). With …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most species do not grow easily in the … years, extracting single cells and then amplifying their DNA for genome sequencing was no easy task. The traditional …
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Better Genome Editing for Bioenergy
A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the … sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized these sgRNAs, cloning …
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Expanding Virophage Diversity
Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant … in  Microbiome , researchers from the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science facility, have increased the number of …
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Axel Visel
Programs, he focuses on the development and implementation of strategic initiatives at the JGI. Dr. Visel received his … Computational Biology , Nucleic Acids Research . Over 80 publications in peer-reviewed journals including Nature, … F, Afzal V, Ren B, Rubin EM, Pennacchio LA (2009). ChIP-seq accurately predicts tissue-specific activity of enhancers . …
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JGIota: A Tool to Find the Nomadic Genes that Help Microbes Adapt - geNomad
A quick snippet on Antonio Camargo and Simon Roux, a few of the JGI researchers behind software that finds plasmids and viruses within microbial … As mobile genetic elements like viruses spread their DNA, they can affect how microbes cycle nutrients and adapt …
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Thawing permafrost, microbes, and viruses: Gary Trubl — Part 1
… wants to understand how viruses impact the release of greenhouse gases from Arctic permafrost. But to see what they’re doing, he first needs their DNA.   …
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JGI Early Career Researchers Featured in mSystems Special Issue
In a special issue of mSystems , out May 14, 2019, JGI researchers are among the authors who offer perspectives on what the next five years of innovation … in soil for the first time. A second approach known as DNA stable isotope probing (DNA SIP) relies on incubating …
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JGI Earth Month: Wetlands Work in #TenHundredWords
April marks both the 50th celebration of Earth Day on April 22, and DNA Day on April 25. As both Earth and DNA are close to our … to living on a changing planet. Mo Kaze is a University of California (UC), Merced graduate student working with  …
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Applying Viral Genomics Expertise to Understanding the Human Virome
… viruses outnumber the microbes by at least another order of magnitude. For years, scientists at the DOE Joint Genome Institute, a DOE Office of Science user facility located at Lawrence Berkeley … involving environmental samples to help uncover the phylogenetic diversity of the human gut microbiome. By …
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JGI announces 2023 CSP Functional Genomics awardees
…   Each year, the JGI accepts proposals for state-of-the-art functional genomics research from potential users … call , we look for projects that will leverage the JGI’s DNA synthesis and omics capabilities to enhance understanding of gene and genome function.  Below find a list of the six …
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
Survey of Setaria's natural diversity reveals seed dispersal in … Center (Danforth Center) drove up and down the highways of the continental United States, occasionally pulling over to the side of the road to collect small weedy plants and bring them …
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