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Extracting the Secrets of Secondary Metabolites
… combo helps further demystify biosynthetic gene clusters.  The Science Microbial secondary metabolites, those … of robust tools available for carrying CRISPR into microorganisms. CRAGE (Chassis-independent Recombinase-Assisted … and other industries — yet there’s still so much about them we don’t know.  Unlocking the power of secondary …
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Gene Expression: From On-Off Switch to Dial
… approach to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of … the realm of bioenergy optimization. Summary Life is all about balance. This study,  recently published in the  … of gene expression and the observable characteristics in an organism. The experiment was led by Hal Alper, professor and …
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Access to Rock Star Scientists
… so nice and helpful.”     Mo Kaze, UC Merced JGI Mentor : Susannah Tringe, Microbial Systems Group “Everyone here is very kind and really open to talking about their work. It’s fun to be around people who are generous with their time and like nerding out about the big stuff, well, the little stuff! People hold …
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Game On: High School Students Drive Everglades Metagenomics Study
Management Group, attended a conference in Florida to discuss a JGI pilot project involving soil sampling in the … the next generation of scientists. She shares her thoughts about the experience below. In the summer of 2018, Jonathan … location because much is unknown about the diversity of organisms (taxonomy) and particularly those in processing …
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JGI Portals
… developments to meet the ever-changing demands of our users. … Download plant, algal, fungal and microbial genomes … tools for comparative genomics of fungi. Mycocosm enables users to navigate across sequenced fungal genomes, and to … generated by the JGI and by others. The web portal allows users to navigate these genomes and conduct comparative and …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… be single bacterial cells, visible to the naked eye. The unusual size is notable because bacteria aren’t usually … newly discovered species of bacteria keeps its DNA more organized. “The big surprise of the project was to realize … explained. “This kind of discovery opens new questions about bacterial morphotypes that have never been studied …
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Gotta Catch 'Em Gall
… called galls.  In this episode, hear from Kasey and Patrick about how this project unfolded, and how they worked with the JGI's metabolomics program to find out more about these weird little pods. …
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Finding the Fermenters
… database of fermentative prokaryotes. The Science Most organisms use oxygen to convert food into energy. However, in … used the JGI’s GOLD and IMG data portals to get information about the genomes and genes of the organisms on the list. …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… domain, there is a group of tiny hitchhikers. These organisms are abundant and yet exceptionally small, with … they need to survive. To fill in their nutrient gaps, they must latch onto a larger host — often, a fellow archaeal … cycling across the planet. Summary To understand more about how archaeal hosts and hitchhikers coexist, …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… analysis leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple … by the Leibniz Institute DSMZ – German Collection of Microorganisms and Cell Cultures GmbH, based in Braunschweig, … information as well as of important descriptive metadata about each strain. “This has been a very fruitful …
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The Case for Conservation
… crop yields.  The Science The fire moss Ceratodon purpureus is a short plant with a complex genome . Now, … and seed yield. Conversely, some crops such as bioenergy sorghum may need sterile males; plant breeding experiments … HudsonAlpha. As the team discussed in a JGI podcast episode about the work, the effort to fully sequence the fire moss …
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When “The Blob” Made It Hotter Under the Water
… began in late 2013, when a large patch of warm ocean water about a third the size of the United States began forming in … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … free-living microbes that can fix carbon dioxide replaced organic matter scavengers. This preliminary model aligns …
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