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… Since joining the DOE Joint Genome Institute in 2016, Dr. … technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … is particularly interested in understanding how, when and why microbes decide to produce which metabolites. …

… user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most … time of publication, it is the largest repository of BGC sequence data from over 1.3 million publicly available … come pre-annotated using multiple commonly used sequence analysis tools is a means of expediting BGC and biosynthesis …

… in their chosen field or fields through the publication of multiple highly cited papers during the last decade” by … umbrella of the GEBA, the JGI is sequencing thousands of bacterial and archaeal genomes from diverse branches of the … Nikos Kyrpides  and Simon Roux — features 600 genome sequences for Actinobacteria.  Woyke  was also one of three …

… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures and … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …

… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … one type of RNA polymerase responsible for each gene. These bacterial RNA polymerases are made up of a core enzyme … the 5’-ends by 5’-end sequencing, from which those promoter sequences recognized by a given sigma factor are inferred. …