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CRAGE-CRISPR combo helps further demystify biosynthetic gene clusters.  The Science Microbial … active secondary metabolites and helping them identify and describe the functions of the biosynthetic gene … highly regulated in bacteria, making it difficult to identify which pathway corresponds to which metabolite. Finding a …

Jarrod Chapman, developed a method to correctly identify polyploid subgenomes without needing to know the genomes … it’s hard to analyze. The ancestors are a bit hard to identify and there’s a small possibility that something could be … on this kind of analysis in more species, as well as modifying this method to study other types of problems …

Atlas in  Nucleic Acids Research . The project spans 15 years and involves more than 17 research groups. The team … Having a better handle on the gene function helps identify the molecular targets for plant improvement. …

… more than once, and these events took place a million years apart: the individual with a maternal  B. distachyon parent (D plastotype) some 1.4 million years ago (Mya), while the S plastotype was a more recent … anticipated with only minor gene loss even after a million years.” Reference genomes for  B. distachyon ,  B. stacei …

… applying a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo … precise genome editing. This means that scientists can modify gene expression, or delete genes, all with the rapid …

… a dark room with a flashlight, only able to clearly identify what falls within that single beam. When it comes to … but we knew the families,” Kyrpides said. Yet, “almost 20 years of metagenomic data and metagenomic analysis, and … of new protein families had started to plateau in recent years, perhaps suggesting that scientists had “captured” …

… viruses is just the beginning. “I often say that just identifying a sequence as viral is not even half the story.” Neri … of efficient, automated approaches to analyze and classify sequence data at this scale is essential.”   … The U.S. …

… in, on, and around the planet remain unknown. In recent years, advances in sequencing technologies and bioinformatic … diverse than those within more moderate ecosystems. A few years ago, a candidate bacterial lineage was identified from …

Unique Capability DAP-seq allows researchers to identify all the sites where transcription factors bind quickly … ENCODE project known as FUNCODE. “We noticed a few years ago that there is no shortage of fungal genomes … functional interpretation is as tough as it has been 10 years ago,” he said. “We thought about reconstructing gene …

… databases. In this case, the machine “learned” to identify a certain type of bacterial viruses or phages called … 70,000 microbial and metagenome datasets, ultimately identifying more than 10,000 inovirus-like sequences compared to … you’ve found the right features that you can use to identify the inoviruses.” Overhauling the Perception of Inovirus …