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We focus our efforts on integrating database mining and sequence design with scaling the production of large, … such as those involving biosynthetic clusters, or high complexity combinatorial libraries.  We have developed … on developing methods for converting digital information from sequence databases into biotechnological or …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … then got funded to work for two years at the Max Planck for marine microbiology in Bremen, Germany. And I wanted to work …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … and so we were able to actually not dive to collect the marine tunicates, which was nice because it’s also cold. And … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… terrestrial biogeochemical processes, development of high performance plants and microbes, and understanding … mass spectrometry-based methods to analyze metabolites from a wide range of biological and environmental samples — … with genomics, transcriptomics, imaging, and other data from EcoFAB systems can provide novel insights into the …

… culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or whatever. And so I was … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? … on plant natural products. Rich, rich in bacterial and marine stuff. So we need more people annotating. It will …

… in the project by watching Amanda Hurley’s presentation from the 2019 JGI Genomics of Energy & Environment Meeting.] … at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

… and bioeconomy applications. The program provides high-quality, large-scale genomic data to advance microbial … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from diverse bacterial and archaeal lineages to improve …

Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, Canada. … Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … with grants funded by DOE-BER requiring support from the JGI may  submit proposals here . Investigators … will develop fuels and products by integrating three highly interconnected DOE priority areas of Feedstock …

… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … in cell biology. 25 (6), 339-346 Schulz et al. (2015) Marine amoebae with cytoplasmic and perinuclear symbionts …

… in the analysis and publication of the claimed genome sequences. This opportunity, provided by the Department of … builds upon thousands of microbial genomes that have been sequenced by the JGI though not formally analyzed or … … A primary purpose of this project is to bring educators from a broad range of disciplines up-to-speed with some of …