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… we don’t recognize, because the only way to find things is by comparison. We’ll talk about that when we talk about … could be a molecule that’s embedded in their – what do you call that – I want to say like lipid bilayer, you know, in … in it. All right, this is probably one of the most famous photographs in microbiology.    ALISON: Oh my gosh DAN: Do …

… single-cell sequencing, resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates … three domains of life. It provides tools for analyzing the functional capability of microbial communities based on … featuring the largest collection of plasmids automatically identified from genomes, metagenomes, and …

… pathways, which led her to a successfully funded JGI CSP project. And we also got to talk about work at her … little bit of your background because you do-- you're classically trained as a synthetic chemist. BETSY PARKINSON: Yes. … based on what component they might be interested in like genomics, metabolomics, just basic chemistry, natural …

… hard it was – it felt kind of like training for a marathon by running at a high altitude! And a lot of us moved on to … because it was too long. Well, when we went looking for a photo of John, we found one from the 70s in the Scripps … of people know who are not specialists, but they’re also called (unfairly) sea squirts, because if you kill them and …

The “Great Plate-Count Anomaly” first described by Stanley and Konopa in 1985, which highlights our skewed … focused on the application of  function-driven single-cell genomics . Here, single cells are characterized and selected as based on a specific functional trait or phenotype of interest, prior to and in …

…   Each year, the JGI accepts proposals for state-of-the-art functional genomics research from potential users who need help … genomic information into biological function. Through our CSP Functional Genomics call , we look for projects that …

… she’s written a book about her life and her science, called The Plant Hunter , and I have to say it’s so awesome! … that morning cup of coffee, that is a plant that has a functional activity. It’s a pharmacological agent that acts … St John’s wort, my immediate thought was, well, what about phototoxicity? And here we have somebody putting this all …

… the quality of single-cell genomes and directly link functional information with individual cells. Research Team  … the first quantitative Stable Isotope Probing (SIP) Metagenomics pipeline that utilizes internal analytical … measure environmental microbiome activity levels.This functional assay lets us move beyond cataloging the genes of …

DAN: Excellent, Yeah. OK, cool. So then what specifically about natural products? What got you in that … it’s really about what are they doing. And so it’s really functional genomics. And there’s a lot of sequencing based approaches, …

Celebrating 25 years of genomics research 2022 marked the JGI’s 25th anniversary. We … to advancing the frontiers of environmental and energy genomics. The two-story mural at the Integrative Genomics Building was painted by Berkeley-based artist Nigel Sussman and dedicated at our …

… a snapshot of microbial diversity and their metabolic functional potential. This research enables us to better … resources that support user analysis of biogeochemically-relevant pathways, enabling modeling of microbiomes … such as quantitative stable isotope probing (qSIP)-metagenomics and metatranscriptomics, to metagenomics and …

… said Susannah Tringe, JGI User Programs Deputy. “These new CSP projects accelerate our efforts to characterize … transformations.” The JGI’s large-scale call included algal genomics as a focus area, and one of the accepted proposals … toward generating “with unprecedented precision” the gene functional networks and regulatory networks of a single …