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… school, then Frances Arnold’s papers came out, directed evolution, and Pim Stemmer. And at the time, I thought that … But then I realized at that point, after doing directed evolution for a few years, that there was also caveats with … by chemical synthesis and make analogs in combination of mutagenesis and direct evolution. Yeah. DAN UDWARY: So it’s …
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Biology is currently experiencing a revolution brought on by rapid developments in genomics and … Unraveling the functional dark matter through global metagenomics. Nature . 622(7983):594-602. Camargo AP. et al. … Cell . 185(21):4023-4037 Nayfach S, et al. (2021) Metagenomic compendium of 189,680 DNA viruses from the human …
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… types to explore the molecular mechanisms behind phenotypic evolution. It also utilizes advanced tools, including deep … accessions) and protocols (transformation, crossing, mutagenesis) are available to the community. … EcoFABs link … It is now available for both eukaryotic and microbial metagenome assemblies. It is also available as an app in KBase …
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… some of the latest developments in microbial genomics, metagenomics, and computational biology, and to empower them … datasets encompassing >150,000 isolate genomes, 230,000 metagenome-assembled genomes (MAGs), and 40,000+ metagenomes along with curated environmental- and other …
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… and another system. There should be. I mean, there’s some evolution that happened. But, you know, bacteria don’t leave … how these particular secondary metabolites arose in evolution? DAN: Yeah, I think the important driver is to … chemical reactions for us. ALISON: And if we understood the evolution of these biosynthetic gene clusters better then we …
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