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… find, things that are of interest. And usually, in terms of bacteria and secondary metabolism, those things that we want … et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in finding … if an order is uncultured (blue; represented only by metagenome-assembled genomes or MAGs) or cultured (gray; …

… a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and … enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the genome. “CRAGE is … of stable, synthetic microbial communities to take advantage of their joint metabolisms. Because, together, microbes …

… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and … metagenomics. Nature Reviews Microbiology volume 20, 721–736 JC Villada, F Schulz (2022) The endosymbiotic box of …

… through the stories I told you about geosmin, which is a bacterial sacred metabolite, and ergot alkaloids come from … maybe obvious or notable. We are still in – not an early stage. I think we can identify most secondary metabolism … but traditionally, somewhere in the neighborhood of 60 to 70% of all of the medicines that we use are natural …

… phages.  Current Opinion in Virology .  49 , 117-126 Berg, M. and Roux, S. (2021) Extreme dimensions — how big … viral infection cycle in wild populations of green sulfur bacteria with long standing virus-host interactions. ISME J. … et al. (2019) Cryptic inoviruses revealed as pervasive in bacteria and archaea across Earth’s biomes. Nature …

… particularly sigma factors that initiate transcription in bacteria. Using this technology, which combines an in vitro … expand the known transcriptional regulatory network in bacteria, enabling the discovery of regulatory cascades as … eukaryotes is handled by three distinct RNA polymerases; in bacteria there is only one type of RNA polymerase …

… been dominated for … well, as long as I can remember, by bacterial research.  So it was great to hear her passion and … lot of the natural products field is based on, you know, in bacterial investigations. You’ve spent your whole career as … do you check if they’re there? Like we always talk about 16S for bacteria, but we don’t talk about it so easily with …

… in Nature and Medicine.” It’s obviously focused more on the bacterial side of the field, and it’s a little hard to find … 3 of the Primer! — DAN: So, you know, in the in the 50s 60s 70s, most of the exploration of this is done by what’s … before. Like, you know, maybe it’s a new culture of a new bacteria that you pulled from the soil, maybe it’s, you …

… work like ActDES, which is a curated database of actinobacteria for evolutionary studies, and hopefully we can … the fungal farms from other fungus that want to take advantage of that resource. So in those type of situations, what … and so on. So I have the feeling that we are just at the stage in which synthetic biology could be making secondary …

… at the University of Hawaii and moved there in the early ’60s from Berkeley to work on this new budding field of … marine natural product biosynthesis and at the beginning stages of connecting molecules and genes. And then genomics … Initially, my group really focused on marine actinobacteria. Then we moved into marine proteobacteria. Not a …

… delicately above the leaf debris are revealed to be single bacterial cells, visible to the naked eye. The unusual size is notable because bacteria aren’t usually visible without the assistance of … Antilles and a co-first author on the study, performed the 16S rRNA gene sequencing to identify and classify the …