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… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … Successful applications will focus on high-risk/high-payoff proposals within the focused topic areas that can be … Accessing Resources at Multiple DOE User Facilities with a Single Proposal describes the resources available from the …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … that – I want to say like lipid bilayer, you know, in the cell.  DAN: It depends on lifestyle. So there are lots of … think of bacteria. You think of bacteria as sort of these single celled organisms, kind of all over. But these kinds …

The mission of the Joint Genome Institute is to serve the scientific … community as a user facility pioneering functional genomics to solve the most relevant bioenergy and … the Letter of Intent; rather proposals are submitted in a single step. … The researcher then submits a proposal for …

… for you here today. We got the opportunity to talk to one of the real legends of natural products, Professor Bill … we want a chemist to study the ocean. And I didn’t find a single job advertisement. But one day, I decided to really … that the molecules out there would be toxic to cancer cells. And that started something big. Because at that time, …

The CSP Functional Genomics call is to enable users to perform state-of-the-art functional genomics research and to help them translate genomic …

… a great opportunity to learn more about JGI, hear some excellent talk from our users and from other invited guests, … about what are they doing. And so it’s really functional genomics. And there’s a lot of sequencing based approaches, … and the stabilized isotope probing work that we’re doing, single cell work we’re doing. And using these together along …

So chemicals are their way of talking. You bring up an excellent point though, and I think this is an area that is a … been shown today is it's more a quorum sensing within a single species. DAN: Within a species. Genus? BETSY … based on what component they might be interested in like genomics, metabolomics, just basic chemistry, natural …

… info about the CSP, FICUS, New Investigator and Functional Genomics calls. For my audience, all of these programs can … molecules obviously play a huge role in ecology through cell-cell communication, chemical warfare, and symbiotic … for example, metatranscriptome sequencing, metagenomics, single cell genomics. We even do the flow cytometry for …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … parasite you really can’t grow well. You have to have it in cell culture. So we are going to see if we can express that … alone – I’m interested in pathogens. It’s just never a single microbe. And we have several recent papers and are …

Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire … The program has been a pioneering effort in functional genomics since 2012, with a focus on addressing critical … bioinformatics tools and genome portals, we study lignocellulose decomposition, CO2 fixation, redox reactions, and …

… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on this the … predict or just understand better the language of microbial cell-cell communication. And he told us about his work in … and they were able to synthesize the genes for every single one of those and put them in individual plasmids and …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … The Secondary Metabolites Program offers users extensive genomics, DNA synthesis and metabolomics capabilities to … (BGCs), advancing pathway analysis, optimization of cell- and cell free-based expression platforms, tools and …