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… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … we can use that knowledge to actually use it in drug discovery, right? I mean, at the end, we somehow have the … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … characterization, the program strives to facilitate the discovery of new bio-based molecules that can drive … factors and determine their binding sites across multiple genomes. Computational prediction of heterologous …

Prodcast episode 17. The guest we have this week is Professor Cassandra Quave from Emory University, with joint … with a broad range of experimental work on plants for drug discovery in antibiotics, anticancer, and now COVID. We also … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … metabolism, has been … not dominated by, but driven by drug discovery. We know that many natural product molecules are … It’s an evolution of primary metabolism. So a lot of the genes and the DNA that’s used for secondary metabolism, they …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … the regulation off, rather than negatively get rid of the genes from their genome. FRANCISCO BARONA-GOMEZ: Exactly … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… … DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took … And so it was very much a co-Dow product.  DAN: Industrial discovery, yeah.  NIGEL MOUNCEY: Right. An amazing product, … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, Canada. … Bill Gerwick as part of the International Biodiversity Drug Discovery consortium doing natural products …

… — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is … and delays on the work. The transfer of a proposal from one commercial institution to a new commercial …

… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS call with EMSL begin with a Letter of Intent (LOI) from a researcher, briefly describing the project …

… (Nature 2016, Science 2017, Nature Microbiology 2018), discovery of new genes with important biotechnological … (2023) Unraveling the functional dark matter through global metagenomics. Nature . 622(7983):594-602. Camargo AP. et al. … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …

Mass spectrometry based metabolomics Below is a table of standard product offerings, including a description of … Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in length, cloned into … and quality of finished product depend on genome. Selected genomes will be improved based on feasibility and scientific …

… constant developments to meet the ever-changing demands of our users. … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic data, open to … host taxonomy, conjugation potential, antibiotic resistance genes, and ecosystem information. … The IMG/VR database …