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… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … chemistry that deals with reactive oxygen species and so potentially could go down that route.  DAN: So the sun … metabolism you know those numbers are still actually pretty high in terms of understanding from just sequence gazing …

… Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples … of sequencing data for synthesis. This agreement, required by the DOE for all work performed in its User Facilities, is … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …

… Data produced and released by the US Department of Energy (DOE) Joint Genome Institute … Data Policy. It is our mission to support open data and information sharing. We also recognize the need to have a … research data and analysis products (referred to as “data” for the remainder of this policy) produced through all user …

… more economic, they also would like to extract some high– what they term “high value–“ Dan Udwary: Right. Kate … see everything, right? You can see the full biosynthetic potential of what you’ve got. Dan Udwary: You might not know … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… and scientists of secondary metabolism. Welcome back for our second season of Natural Prodcast. This first … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … but in subtle ways that affect fitness. And so, doing a high level kind of analysis, you just might not be able to …

… and SIO. Oh, I should say what those are. Brad: What’s SIO, for all those listeners out there? Dan: Scripps Institution … two sequenced genomes of a Streptomyces , or gram-positive high GC organism.  Dan: Yeah, not a lot of natural product … might make this molecule and predicting what kind of enzymes might be involved, and then being able to make those …

… sparked your interest, and you want to learn more, then I highly recommend David Hopwood’s book called  “Streptomyces … it’s a little hard to find in print, but we live in the information age and the ebook version is available at most … Right. Yeah. DAN: Alright, so a subset of proteins are enzymes. Enzymes are proteins that do chemical reactions. …

… The Facilities Integrating Collaborations for User Science (FICUS) call represents a unique … research proposal.  Successful applications will focus on high-risk/high-payoff proposals within the focused topic … provides customized analysis, the JGI also participates in publication of results. …

… bioenergy solutions.  The program has been a pioneering effort in functional genomics since 2012, with a focus on … by synthesizing genes, pathways, and whole chromosomes for bioenergy and bioproduct applications. The program has … tools that enhance biofuel production and biosystem design. High-throughput design and synthesis capabilities accelerate …

… and microbiology just followed me all the way through my high school days in England.  DAN: What did your dad do in … products work, right? Think about how many things that are potential drug molecules that have micromolar activities. … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

…   Overview of sequencing products The JGI operates highly scaled short- and long-read sequencing pipelines. … An assay used for profiling transcription factor binding sites across … to a multiplexed DAP-seq (multiDAP-seq) method allowing high-throughput processing of samples in 96-well plates on …