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… genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … clusters across different species, which all encode the production of either the same or similar molecules. And then … with sequence similarity, either we just looked at which protein domains are in a gene cluster or we did sequence …

… of secondary metabolism.  DAN: Hey there and welcome back for Episode 8 of Natural Prodcast. This week, we have our … on this: Most of the machinery in any living organism are proteins, which are made up of chains of amino acids. “Peptide” is just another word for a small protein. And it turns out that a lot of natural products are …

… and the bacteria and how the chemistry is going back and forth between them is part of what fascinates me about what … community itself works together to elicit new metabolite production. And we are also interested in how the jelly … easy to search for because there are patterns of domains, protein domains that you look for. And if you find those all …

… and scientists of secondary metabolism. Welcome back for our second season of Natural Prodcast. This first … itself medicine, but the coding within the DNA codes for proteins that do the chemistry that put molecules together … oxidative conversions and do some really complicated carbon skeleton rearrangements, chemistry that we probably …

It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for the … does all kids of things around nuclear security, energy production, and scientific research, especially at US … and work within the DOE emission space of bioenergy, carbon cycling, biogeochemistry, bioproducts. So we cannot …

Takemura, whose voice you’ll hear in a minute – we work for the US Department of Energy Joint Genome Institute, or … Now, we didn’t get into secondary metabolites really in my studies. So this is, is an area that was adjacent to what I … pathways of pink and teal, and Dan pointed out the Krebs cycle to me earlier – I kind of see it. DAN: So what we’ve …

… material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from … genomes are critical to serve as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic potential of …

See below for examples of successful Letters of Intent to our … Genomics, and Facilities Integrating Collaborations for User Science calls. These documents have been shared … metabolic flexibility? … Microbial contributions to soil carbon storage during simulated range shifts of plant-fungal …

I wanted to tell you about in this introduction. First and foremost, our interview this week is with Professor Brian … where he is the PI of the Laboratory for Biosynthetic Studies. Brian and I are old friends and colleagues, having … or you could look at metabolism markers like phosphoprotein S6. So if there is a perturbagen present– DAN …

… … Dan Udwary: Hey everybody! Welcome back for Natural Prodcast episode 17. The guest we have this week … screen to look at the interaction between SARS-coV-2 spike protein and the ACE2 receptor, so we’re looking at viral … plant natural products is rife with really poorly designed studies. We have studies where people write about work on …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I … we recorded in my hotel room at SIMB, or the Society for Industrial Microbiology conference that took place in … environmental roles of these compounds? Can we perform studies such as looking at the distributions of different …