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Natural Prodcast Episode 14: Nigel Mouncey
… DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took … had two major natural products projects that we had in my group which was bioengineering bio-process R&D, BBRD, a … up to supporting 200,000-liter fermenters.  DAN: Was that discovered there or did it start–  NIGEL MOUNCEY: The …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… freely within the cytoplasm of their cells. This newly discovered species of bacteria keeps its DNA more organized. … studying Ca. T. magnifica in Tanja Woyke’s Single Cells Group to better understand what this sulfur-oxidizing, … in more details. These techniques allowed him to observe novel, membrane-bound compartments that contain DNA …
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Metabolomics Program
… The JGI’s Metabolomics Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to enhance our understanding of genome science, organisms, and ecosystems at the … genomics with metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables …
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Novel Z-DNA binding domains in giant viruses.
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Virus Discoveries that Keep Getting Bigger
… years, in environments all over the world, scientists have discovered giants among viruses. Now categorized in their … the diversity of the  Nucleocytoviricota phylum. As a group, giant viruses infect a wide array of microeukaryotes, … In 2020, a JGI-led team used this approach to deliver novel viral genomes from freshwater, sewage, and marine …
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Natural Prodcast Episode 22: Alison Narayan
… Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … this question, we have this discussion internally in my group quite frequently. OK, so imagine this sentence comes … students to work in my group, it looked like he had like a giant thing of like candy corn on his bench. And I was like, …
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Strain Engineering
… The focus of this group, in recent years, has been to bring … The developed strains represent an additional phase of user-accessible project types, in which DNA-based … chromosomally integrated into a taxonomically diverse suite of microbial chassis strains for elevated opportunity for …
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Natural Prodcast Episode 17: Cassandra Quave
… love and care. Yeah, and let’s see. I lead a research group at Emory, I teach classes here on food and health and … use successfully, hopefully, in the future even more so as novel therapies. And that’s how I got on that path of … now. But was there any reward to the people that originally discovered how coffee could be used?  The same can be said …
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Mining New Frontiers: The Critical Minerals and Materials Joint Call
… for researchers to request the capabilities and expertise of both national user facilities in one research proposal.  … challenges in the sourcing, recovery, and utilization of critical minerals and materials. The proposal submission … Access to the Molecular Foundry and use of JGI capabilities is free. The JGI supports remote users. …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … machine learning really would help distinguish and predict novel gene clusters. DAN UDWARY: Yeah, it certainly could. … small peptide. So at a certain point, a couple of different groups noticed that they could take all of these adenylation …
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Natural Prodcast Episode 8: Eric Schmidt
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … student, and he told me if I wanted to get into his group that I would have to cut it, and so I came in the next … a few projects on sponges. It’s an area – there’s some good groups around the world that focus on sponges. And so I feel …
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Natural Prodcast Episode 2: The Primer, Part 2
… One of the organisms that I studied in the past were a group of bacteria called the Frankia . And so the Frankia … often use primary metabolites as building blocks to produce novel molecules. And so we’ve got glycosides being made into … of the plate that Alexander Fleming produced when he discovered – or was on the road to discovering – penicillin. …
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