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… capture microbial and viral diversity, leading to a better understanding of microbial communities and ecosystem … Our research focuses on the assembly of metagenomic sequence data into microbial genomes, which is of … gain insights into microbial interactions, evolution, and adaptation, ultimately informing strategies for environmental …

… in synthetic chemistry as were you and then made their way into the field of natural products in some way, shape, or … [project] with JGI, how many flavin monooxygenases are you sequencing, sort of along that vein, of if you have one or … could have arisen from. DAN UDWARY: OK, so sort of a phylogenetic reconstruction kind of a thing. ALISON NARAYAN: …

… focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such … that are from candidate phyla, major branches in the phylogenetic tree without cultivated representatives. The “Great … by Stanley and Konopa in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of …

… than it is now. Or a little more– yeah, put more rationale into drug discovery by knowing what these things actually do … I think. DAN UDWARY: Yeah, and that was a JGI Community Sequencing Project. You’re right, yeah. NADINE ZIEMERT: Yes. … actually can learn just by really digging into the data and understanding what’s going on there. And now, that’s all I …

… basic ideas of the science of natural products, and we dive into the very early history of the field. If you continue … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have … changes that nature has made. So secondary metabolism is adaptation of primary metabolism. They’re duplications of the …

… which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … episode with her in the near future where we can dive into that. And I’m also dying to talk in more detail about … in everninomicin and analogs of that, you’re really understanding one specific biosynthetic pathway. I guess how …

… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … producing molecules that are helpful to the plants. And so, understanding those broader environmental and ecological … worked is people who were trying to find gold would go out into the hills. And they knew from example that gold is a …

… granting access to diverse datasets that deepen our understanding of how organisms interact with each other and … access and analyze data on scales ranging from single genes and individual genomes to metagenomes to systems-level modeling and understanding. JGI and KBase are designated DOE Office of …

… Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, … the program enables the design and synthesis of complex genetic pathways and biosystems. It The program fosters … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of …

… partnerships in developing countries for research into various aspects of biodiversity, of which natural … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire … in lots of areas, we would like to do a better job of understanding gas phase reaction mechanisms. We would like …

… Linking lignin engineering to drought stress resilience: RNA-seq and metabolomic insights in lignin biosynthetic pathway … Elucidating Sphagnum microbiome genetic interactions for improved growth at elevated … Adaptive strategies in a cosmopolitan and abundant soil …

… hands-on learning opportunities and ultimately, an understanding of the JGI’s role in enabling complex … at UC Berkeley is a program designed to foster a profound understanding of research methodologies within the realm of …