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2024 Progress Report
… also co-located in the IGB. Vision  Lead genomic innovation for a sustainable bioeconomy. Mission  As a U.S. Department … April 2024 — through serving an increased number of users with a record output of products, making data easier to … number of primary users — 2,475 — had active proposals with us, along with more than 15,000 secondary users who …
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Synthetic Biology Lab
… technologies to the broader community.  We focus our efforts on integrating database mining and sequence design with scaling the production of large, difficult to … ever-higher levels of throughput. We also develop methods for efficient QA/QC based on next-generation sequencing …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple applications … a decade, researchers around the world have collaborated with the U.S. Department of Energy (DOE) Joint Genome … senior author of the study and head of the JGI’s Microbiome Annotation Group. Many of these bacterial and archaeal …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
In 2009, researchers at the JGI and the Bigelow Laboratory for Ocean Sciences described a novel technique to access high-quality genomic information using minute quantities of DNA derived from … study built off earlier approaches and offered a way for researchers to study the planet’s microbial diversity, …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… of 100 times the size of what has typically been associated with viruses, while the genomes of large viruses may be only … viruses (NCLDV) supergroup. The expansion of the diversity for large and giant viruses offered the researchers insights into how they might interact with their hosts, and how those interactions may in turn …
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JGI@25: Studying Sorghum’s Survival Skills
… challenges. Sorghum stands out as a candidate feedstock for biofuels thanks to its drought and flood hardiness. Even with little water, full sunlight and hot temperatures, … Genome roster. Sorghum has an important feature in common with certain other cereal crops: It performs C4 …
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You Can Move, But You Can’t Hide
… and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found in … at Lawrence Berkeley National Laboratory (Berkeley Lab), with computing resources provided by NERSC, another user … understand ecosystem-wide processes. Summary geNomad is an annotation and classification framework that combines and …
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JGI@25: Building a Better Bean
… in soil health through nitrogen-fixation and holds clues for maximizing soybean, the common bean’s close relative, as … . “Common beans are a major societal crop for those with severely limited income,” McClean said. “Common bean is … America and Eastern Africa. For smallholder farmers — those with less than two hectares of land — common bean is often a …
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Three Join the JGI User Executive Committee
… and Elizabeth “Lizzy” Wilbanks of the University of California, Santa Barbara. They join eight other JGI users … lead on PNNL’s Soil Microbiome SFA. She serves as Secretary within the Microbial Ecology Section of the Ecological … in crops. He has been a PI or Co-PI on five user projects with the JGI, as well as served on review panels for the JGI …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… some archaeal hosts and their hitchhikers. The Science Within the archaeal domain, there is a group of tiny … These organisms are abundant and yet exceptionally small, with mini genomes to match. As a result, they cannot process … how these hosts and hitchhikers coexist is key for understanding their impact on wider ecosystems, but …
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The exceptional form and function of the giant bacterium Ca. Epulopiscium viviparus revolves around its sodium motive force
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JGI announces 2024 New Investigator portfolio
The JGI is eager to work and share our tools with a widening circle of researchers. That’s why each year we look for novel research projects — aligned with DOE missions and from PIs who have not led any …
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