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Boosting Small Molecule Production in Super “Soup”
… still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have … , researchers led by Hal Alper at The University of Texas at Austin and Michael Jewett of Northwestern University describe a two-pronged approach …
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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory protein. Researchers demonstrated the efficacy and potential of regulon identification by in vitro … This work was supported by the U.S. Department of Energy Office of Science under Contract No. …
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Boosting Small Molecule Production in Super “Soup”
… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … an alternative format for chemical synthesis in the absence of cell growth by isolating the soluble components of lysed cells. By separating the production of enzymes …
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Gene Expression: From On-Off Switch to Dial
… to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene expression allowed researchers to identify variations of essential genes in metabolic networks that were missed … This work was funded by the Air Force Office of Scientific Research under Award No. …
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Toward More Efficient Artificial Photosynthesis
… (MPI) for Terrestrial Microbiology and the University of Bordeaux have developed a platform that mimics … composition variants. Summary In the  May 8, 2020 issue of  Science , a team led by Tobias Erb, director of the MPI for Terrestrial Microbiology, successfully …
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JGI Hosts GPU Hackathon in May
… Computing Facility (OLCF), NVIDIA, and the Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user facility, aims to explore applications in …
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Team Science Reveals Important Protein in Poplar
… Described as the “DOE Tree,” poplar is considered one of the  Flagship Plants for the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley … This work was supported by the U.S. Department of Energy, Office of Science, Office of Biological and …
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Alabama A&M Interns Access An Abundance of Knowledge
… the DOE Joint Genome Institute and Alabama A&M University piloted an internship program to bring students to the JGI … mentors Yi Zhai and John Vogel on researching the effects of Brachypodium distachyon plant root exudates on the plant … is Dr. Yi Zhai, and I’m currently working on the effect of plant root exudates in the rhizosphere and microbiome. …
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An Inside Look at How Plants and Mycorrhizal Fungi Cooperate
… A new view into a symbiosis could offer benefits to address climate change: pulling atmospheric carbon into soil and boosting biofuel feedstocks with less fertilizer. For millions of years, underground fungi have lived in symbiosis with … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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JGI Earth Month: Kjiersten Fagnan Reflects on Shelter-in-Place Effects
… In   April 2020, we mark both the 50th celebration of Earth Day on April 22, and DNA Day on April 25.  On March … at Lawrence Berkeley National Laboratory, is located in one of those counties. The shelter-in-place order has since been … In this brief captioned video, JGI Chief Informatics Officer Kjiersten Fagnan reflects on the personal and …
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Engagement Webinar: How to Apply for Resources at Multiple DOE User Facilities
… just one research proposal. Guest speaker Michelle O’Malley of UC Santa Barbara talked about how her approved FICUS … Collaborations for User Science” (FICUS) program. Letters of Intent are due March 17, 2021. Q&A from the Webinar: … on the proposal call page. Feel free to  reach out to any of them with questions. Q:  Apart from instrumental support, …
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Webinar: Introducing the BioSANS capability
… on “Integrated Multi-omics Analyses for the Prediction of Metabolic Flux in. Lignin Conversion”       … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility  located at Lawrence …
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