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A Community Resource for Secondary Metabolite Researchers
… more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence … over 1.3 million publicly available bacterial and archaeal genome and contig sources.  The Impact Secondary metabolites … repository of BGC sequences that come pre-annotated using multiple commonly used sequence analysis tools is a means of …
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Examples: Successful LOIs & Submissions
See below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, as well as successful submissions to our …
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Doubling Down on Known Protein Families
… of scientists at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … Laboratory (Berkeley Lab), and collaborators across multiple other research centers around the world. “We’ve … and the functions they perform, artificially replicating a whole community is impossible.  Metagenomic sequencing …
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Comparative genomic and physiological analysis provides insights into the role of Acidobacteria in organic carbon utilization in Arctic tundra soils
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JGI@25: Studying Sorghum’s Survival Skills
… climate has earned it a place on the JGI’s Flagship Plant Genome roster. Sorghum has an important feature in common … reference genome for Sorghum bicolor . Since then, 2,993 publications, 107 patent applications, and 53 patents have … projects at the JGI: 2009: JGI and collaborators use whole-genome shotgun sequencing to analyze the 730-megabase …
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Computationally Classifying Fungal Lifestyles
Machine learning methods were applied on sequenced fungal … (From Haridas S et al.  Studies in Mycology , 2020.) Using whole genome data from newly sequenced genomes, they also …
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Whole metagenome sequencing and 16S rRNA gene amplicon analyses reveal the complex microbiome responsible for the success of enhanced in-situ reductive dechlorination (ERD) of a tetrachloroethene-contaminated Superfund site
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Better Genome Editing for Bioenergy
A team has optimized a crucial part of CRISPR-Cas9 … included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … cut, but these “single guide” RNAs (sgRNAs) can be faulty. Without a good sgRNA, Cas9 is ineffective and leaves the …
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Fishing for Novel Cellulose Degraders
A “bait and hook” single-cell genomic approach to … by Tanja Woyke at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … sorting to sort cells into several small pools, followed by whole genome amplification and shotgun sequencing. The team …
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BdERECTA controls vasculature patterning and phloem-xylem organization in Brachypodium distachyon
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Characterizing Communities: JGI Announces Latest CSP Portfolio
Proposals aim to sequence and annotate genomes from Antarctica to … of West Africa. The staple crop there is millet, grown without fertilizer and under erratic rainfall conditions. To …
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Len Pennacchio
In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused … technical JGI directions for DOE User science. … Complete Publications Genomic Technologies Program Defining the vast …
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