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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… communities than ever before — especially with the prospect of meta-analyses boosted by AI and Machine Learning — JGI … communities. By pairing RNA or DNA sequencing with tracings of stable, heavy isotopes, SIP allows researchers to go … this was the first workshop of its kind on SIP metagenomics,” Malmstrom said.  Increasingly, efforts like these …
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Hiroshi Otani
… technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo PhD, Biotechnology, University of Tokyo … Udwary DW, Mouncey NJ. Comparative and pangenomic analysis of the genus Streptomyces. Sci Rep. 2022 Nov 7;12(1):18909. …
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Benjamin Cole
… University of California, San Diego (PhD, 2011) Rensselaer Polytechnic … List of pubs available on NCBI … Implementation of the Index of Cell Identity as an R package … Selected Publications … Software …
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Yasuo Yoshikuni
… Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, strain engineering, and biosystems design … at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.  …
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Ben Bowen
… BS – University of Arkansas, Fayetteville, Chemical Engineering Ph. D. – … 2024 Berkeley Lab Recognition of Excellence Award 2016 R&D 100 Winner 2014 Berkeley Lab … T., Ruebel, O., Northen, T., & Bowen, B. (2015). Analysis of metabolomics datasets with high-performance computing and …
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Kjiersten Fagnan
… closely with staff to understand the data-intensive nature of JGI workloads. Dr. Fagnan was appointed CIO of the JGI in 2016, and in 2018 was hired to be the JGI’s … Methodologies workshops. In 2018, Dr. Fagnan was part of the Gordon Bell prizewinning team at the Supercomputing …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… is not exclusively for Euryarchaeota. Atmospheric levels of methane, a potent greenhouse gas, regulate Earth’s … Euryarchaeota .  Finding Methane-Making Microbes with Metagenomics  By leveraging metagenomics to sample the entirety of a microbial community out …
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Honey Bee Gut Microbiota Divvy Up Dinner
… Scientists find bee gut microbes have a division of labor when it comes to metabolizing complex … One other finding that interested the authors was that an evolutionary analysis of  Bifidobacterium strains in honey … don’t make honey; they hibernate in winter instead. So, evolutionarily, it might make sense that honey bees have a …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… JGI-led team significantly expands the global diversity of large and giant viruses. While the microbes in a single drop of water could outnumber a small city’s population, the … co-cultivated with amoeba or with their hosts, though metagenomics is now making it possible to seek out and …
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JGI Earth Month: Kjiersten Fagnan Reflects on Shelter-in-Place Effects
… In   April 2020, we mark both the 50th celebration of Earth Day on April 22, and DNA Day on April 25.  On March … at Lawrence Berkeley National Laboratory, is located in one of those counties. The shelter-in-place order has since been … In this brief captioned video, JGI Chief Informatics Officer Kjiersten Fagnan reflects on the personal and …
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Accelerating Metagenomics Discoveries with Deep Learning
… insights from metagenomic data. In deep learning, a branch of machine learning, data is passed through algorithms … into multiple interconnected layers. The architecture of these algorithms, inspired by communication networks … found in nature, allows machines to “learn” features. State of the art algorithms can perform astonishing degrees of …
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Engagement Webinar: How to Successfully Apply for a CSP Proposal
… and relevance to the DOE’s mission.  Have someone proofread your proposal to make sure the goals, experimental … the 500-gigabase cap and that you don’t request outside of the sample range that’s listed. Q: What are the pros and cons of proposing a truly exploratory small proposal that might …
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