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Trent Northen
… Northen’s research is focused on using metabolomics to link genomes with environments to understand how webs of microbes … Wang G et al. Chassis-Independent Recombinase-Assisted Genome Engineering Enables Rapid Activation of Biosynthetic … Selected Publications …
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A Plant Root Atlas for Tracking Developmental Trajectories
… scientist at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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You Can Move, But You Can’t Hide
… MGEs based upon their gene content and their genetic sequences. The software was created by researchers under the … Lead Nikos Kyrpides at the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility at … Resource (IMG/VR) , now with more than 15 million viral genomes. It was also key to developing the first version of …
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How Maize Makes An Antibiotic Cocktail
… infection. They analyzed differences among mutant maize strains, deploying gene editing to knock out four critical … synthesized by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … 1758976 to E.S. and P.Z.) for diterpenoids, by a DOE Joint Genome Institute Community Science Program (JGI-CSP) grant …
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Promoting the Power of Viral Metagenomics
… hydrothermal vents – and computationally identifying which sequences represent viruses that were present in the sample. … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Hiroshi Otani
… Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying … Publications …
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Building Wet and Dry Lab Skills
… of Alabama A&M University students coming to the DOE Joint Genome Institute for research and training experience funded … My name is Yi Zhai. I'm a project scientist at Joint Genome Institute. And, also the mentor, for Zyiah and …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… coherent pieces called contigs — into genes and even into genomes — from these environmental samples,” said Matthias … of rumen-digested switchgrass, researchers isolated and sequenced DNA from rumen microbes involved in the digestion … how JGI data supports higher education in this JGIota , a Genome Insider podcast minisode.)  “The ultimate target has …
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What Happens Underground Influences Global Nutrient Cycles
… Molecular Sciences Laboratory (EMSL) and the  DOE Joint Genome Institute (JGI)—have selected 11 proposals for … alga  Chlamydomonas reinhardtii , one of the JGI’s Flagship genomes. She and her colleagues have generated a … their FICUS proposal include assessing the distribution of genome-derived functional traits through the soil profile …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… Researchers with the Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user … that precisely maps where transcription begins on the genome. This revealed a sweeping cellular response: The … The team also identified previously unknown promoter sequences within these gene clusters, offering new …
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Streamlining Regulon Identification in Bacteria
… in Streptomyces coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions … of the mission of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … the 5’-ends by 5’-end sequencing, from which those promoter sequences recognized by a given sigma factor are inferred. …
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A Natural Mechanism Can Turbocharge Viral Evolution
… ago, a team discovered a group of viruses that had in their genomes a surprising tool: a “diversity generating … by scientists at the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user … these DGRs. DGRs were found in single microbial and viral genomes, as well as genomes sampled all at once from the …
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