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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… before. In 2006, the JGI produced 33 billion base pairs of sequence; by 2023, that number was almost 717 trillion. Last year, the JGI surpassed three Petabases of data sequenced — that’s three-quadrillion base pairs of DNA sequence! To meet this “ data tsunami ,” as Kathy …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… a microbial mat. The Science In microbial mats, communities of microorganisms live among viruses that infect them. But … interactions? Do generalist viruses run rampant, capable of infecting different host species? Or, do they tend to … virus in 34 hosts or 26 percent of the single cells. Metagenomics sequencing then allowed the team to ask, for the 34 …
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Supercharging SIP in the Fungal Hyphosphere
… The Science Researchers have successfully automated aspects of a commonly-used process for studying microbial … with results published in the  November 2022 issue of Microbiome . High-throughput stable isotope probing (SIP) … and improve results. Applying this method to the study of a particular fungi, researchers identified novel …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… di-GMP (Guanine Monophosphate) is found in nearly all types of bacteria and interacts with cell signaling networks that … role in regulating microbial cellulose production and biofilm formation, which affects a number of environments, including plants, soil, and the gut. To …
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iPHoP: A Matchmaker for Phages and their Hosts
… With metagenomic sequencing, researchers have found more of these viruses than ever before, in all kinds of ecosystems. However, matching these viral genetic … integrated prediction a confidence score. The result is a genus-level host prediction tool that draws on the strengths …
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Identifying the Microbial Cleanup Crew at a Superfund Site
… PCE (perchloroethylene) found its way into the groundwater of several communities in New Mexico via leakage from a … bioremediate toxic substances has led to the development of cost-effective environmental cleanup strategies. Summary In New Mexico, the city of Española, the Santa Clara Pueblo and its nearby rural …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… Science Altiarchaea are carbon-fixing microbes and targets of multiple viruses in Earth’s deep subsurface. They are abundant representatives of deep subsurface ecosystems. A team of researchers … by combining a study of microbial communities (metagenomics) and a chemical labelling approach. The Impact …
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Team Science Reveals Important Protein in Poplar
… Described as the “DOE Tree,” poplar is considered one of the  Flagship Plants for the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley … This work was supported by the U.S. Department of Energy, Office of Science, Office of Biological and …
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