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How to Target a Microbial Needle within a Community Haystack
… make-up of specific uncultivated microbes from complex environmental samples. The Science A team led by researchers at … and then efficiently retrieve and characterize their genomes. The Impact Despite great strides in generating genome sequences for members of the microbial world through …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… polar oceans give rise to some of the largest food webs on Earth. And at their base are microscopic, photosynthetic … important cold-water communities of algae with warm-adapted ones, a trend that threatens to destabilize the delicate … UEA and including the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring … Researchers with the Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user … that precisely maps where transcription begins on the genome. This revealed a sweeping cellular response: The …
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Streamlining Regulon Identification in Bacteria
… RIViT-seq technology could speed up associating transcription factors with their target genes. The Science Regulons are … in Streptomyces coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions … of the mission of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… In microbial mats, communities of microorganisms live among viruses that infect them. But what trends govern those … lysogeny, they can insinuate themselves inside the host’s genome, living quietly and replicating with their host … researcher at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Nandita Nath
… Nandita is involved in developing new methods to improve genome recovery from single cells and to build sequencing … libraries from minimal DNA input without amplification. …
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JGIota: Looking Back at Sequencing for Soybeans
… fields. So in 2010, the JGI helped publish the original genome sequence for the soybean, Glycine max. With a full genome sequence, researchers have been able to look into soybean’s strengths – along with a fungus that threatens this important crop. Hear …
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A Plant Root Atlas for Tracking Developmental Trajectories
… zu Berlin   has developed an atlas that maps gene expression patterns in the  Arabidopsis root, profiling nearly … scientist at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … Phytozome and will be available for future single-cell projects.” The Berkeley Lab  Biosciences Area has been …
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Danielle Goudeau
… combines custom flow cytometric analysis, cell sorting, genome amplification, PCR screening, and 16S sequencing. She also develops …
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Alabama A&M Interns Access An Abundance of Knowledge
… In 2024, the DOE Joint Genome Institute and Alabama A&M University piloted an … DOE RENEW initiative, undergraduate student Ti’Yanna Watson and graduate student LaMonika Dent worked with JGI mentors Yi Zhai and John Vogel on …
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Hiroshi Otani
… Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in microbes, particularly actinomycetes. His research activity is focused on developing and implementing new technologies and … H, Mouncey NJ. RIViT-seq enables systematic identification of regulons of transcriptional machineries. Nat Commun. …
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Biotech Partners Summer Intern Co-Authors NAR Paper
… Kaushal Sharma, one of five Antioch High School rising juniors who participated in internships at the DOE Joint Genome Institute this summer through the Biotech Partners … the version 6 data updates and feature enhancements to the Genomes OnLine Database (GOLD) administered by the DOE JGI. …
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