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Fishing for Novel Cellulose Degraders
A “bait and hook” single-cell genomic approach to bioprospecting. The Science One of … specific catches. A similar technique has been developed by researchers led by Tanja Woyke at the U.S. Department of … To validate the predicted cellulases from their captured genomes, the team then used DNA synthesis and cloning, …
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… last 40 years, summer sea ice in the Arctic has decreased by more than 30% in terms of quantity and thickness. … several points in time to assess nutrient concentration and cell death. Immediately upon transfer, the experimental … significant stress with a higher proportion of dead cells recorded. Samples were taken again at two, six, 12 and …
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What Happens Underground Influences Global Nutrient Cycles
… alga  Chlamydomonas reinhardtii , one of the JGI’s Flagship genomes. She and her colleagues have generated a … mutant library in Chlamy, as the alga is colloquially known by researchers. A missing gene from this mutant library … group, one of the four proposals selected is led by Eoin Brodie of Lawrence Berkeley National Laboratory …
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Synthetic Biology Informatics Group
… a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… page of that book. Published online September 28, 2022, in Cell , a team led by researchers at Tel Aviv University in Israel, the … datasets from the JGI’s Integrated Microbial Genomes & Microbiomes (IMG/M) system. “We then looked into …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
Rumen microbes have the ability to break down hardy plant cell walls and therefore hold clues to how humans could do … scientists to study microorganisms that can’t be cultured by analyzing and then extrapolating data obtained from … coherent pieces called contigs — into genes and even into genomes — from these environmental samples,” said Matthias …
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JGI@25: Using Team Science to Build Communities Around Data
… in 29 U.S. states and 35 countries. (Graphic: Neil Byers) The JGI launched the 1000 Fungal Genomes (1KFG) Project through a 2012 Community Science … State University led the effort to sequence 1000 fungal genomes to create two reference genomes for all fungi …
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IMA genome-F18
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How Filamentous Fungi Sense Food
… model fungus  Neurospora crassa . The Science A team led by researchers at the University of California, Berkeley … decide on the order in which this fungus breaks down plant cell wall materials including lignin, cellulose and … enriching the work being done as part of the 1000 Fungal Genomes Project. Funding for the project was also provided …
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CalTeach
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JGI@25: The Little Alga That Could
… and environmental challenges. Chlamydomonas is a single-celled alga with a unique place in evolutionary history. … 7,000 genes with other organisms (a third of those shared by both humans and flowering plants). Its genome also … impact. Her lab has sequenced four additional green algal genomes using Chlamy as a reference for functional …
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Making a Lichen Together
For the first time, a team has analyzed in parallel the genomes and transcriptomes of both partners to better … are able to partner to form lichens. Studying the symbiosis by investigating a lichen’s genomes and transcriptomes could … the fungus and alga, either separately or together, on nitrocellulose filters in Petri dishes. The scientists also …
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