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Statement on the Use of Genomics Data
… The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is committed to … are requested to be held until a specified date, or the publication date, whichever comes first. For nearly 40 … by the community regarding the use of JGI data prior to publication by the principal investigators. To resolve these …
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Boosting Small Molecule Production in Super “Soup”
… Do metabolic pathways from engineered yeasts still work in cell-free … Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … Lawrence Berkeley National Laboratory, indicates metabolic pathways could be more productive outside the cell …
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Gene Expression: From On-Off Switch to Dial
… library approach to tuning gene expression in metabolic pathways. Compared to the traditional way, which leverages … to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene … The Impact Metabolic engineering could lead to sustainable pathways for making high-value bioproducts including …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under … coelicolor to activate multiple chemical production pathways. By tracking gene activity and chemical output over … specific genes, regulatory elements and metabolic pathways that enable that shift provides engineers concrete …
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Picking Up Threads of Cotton Genomics
… growing on plants, with fluffy white bolls bursting out of the green pods in every direction. There are 100 million … on cotton production, and the crop’s annual economic impact of $500 billion worldwide underscores its value and … Science “The results described in this  Nature Genetics publication will facilitate deeper understanding of cotton …
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A Sorghum Pangenome Opens More Doors to Discovery
… Leveraging decades of technological development, dozens of reference genomes and thousands of resequenced sorghum … Development (USAID) also supported the work.   Publication:  Morris, G.P., Harder, A.M., Healey, A.L.  et … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Biotech Partners Summer Intern Co-Authors NAR Paper
… Kaushal Sharma, one of five Antioch High School rising juniors who participated … program is now an author on a Nucleic Acids Research publication. The paper describes the version 6 data updates … in GOLD. “Besides these, he curated several small sets of phylogeny, biosample metadata tasks we assigned.”       …
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JGI Portals
… expertise and infrastructure enable a broad community of scientists and engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data discoverability and … the JGI will move to a new login service, requiring the use of an ORCID account with two-factor authentication enabled …
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JGI Earth Month: The Unusual Metabolism That Helps Plants Withstand Drought
… In April 2020, we mark both the 50th celebration of Earth Day on April 22, and DNA Day on April 25. As both … in between.  KAROLINA:  Plants can use a little bit of both pathways. Some plants can appear to be almost entirely C3, … where plants are using a little bit of both of the pathways.  ALISON: Karolina studies these CAM-C3 hybrids. …
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JGI announces 2024 Functional Genomics awardees
…   Each year, the JGI accepts proposals for state-of-the-art functional genomics research from reseachers who … synthesis and omics capabilities to enhance understanding of gene and genome function. Tapping into these functions … and developing high-throughput methods to reveal metabolic pathways that could ultimately enable new or more efficient …
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SPRUCE-ing Up Science
… his backyard in Tennessee — the birds are chirping and a soft breeze ripples through the trees in his backyard. Originally from northern California and one of the first students to participate in the DOE Joint Genome … fine tune his approach. “I got a lot of that from Zhong.”   Publication: Carrell AA et al. Habitat-adapted microbial …
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How Maize Makes An Antibiotic Cocktail
… Maize produces a family of compounds that protects it against infections — using … enzymes. The Science Maize ( Zea mays ) produces a plethora of antibiotics called zealexins. Even though scientists have … that maize synthesizes these compounds via clear, straight pathways, entailing the function of more than a dozen …
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