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Boosting Small Molecule Production in Super “Soup”
… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … an alternative format for chemical synthesis in the absence of cell growth by isolating the soluble components of lysed … Rapid Prototyping of Genes and Pathways” at the JGI Annual Genomics of Energy & Environment Meeting on September 1, …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the genome. “CRAGE is central to our ability to offer host-engineering for our users,” says JGI Director … as part of the Community Science Program (CSP)  Functional Genomics proposal call. …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… characteristics — creating many different ways of processing nitrogen. To boost crops more efficiently in … — they rely on enzymes that have been evolving for billions of years. However, these enzymes are often loosely … Korea as well as a faculty affiliate in the Environmental Genomics and Systems Biology Division of Lawrence Berkeley …
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Building Wet and Dry Lab Skills
… Summer 2025 marked the second year of Alabama A&M University students coming to the DOE Joint … experience funded by a DOE training grant.  Building off the previous year’s project, undergraduate interns … mentors Yi Zhai and John Vogel from the Plant Functional Genomics Group to study the effects of  Brachypodium …
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Hiroshi Otani
… technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo PhD, Biotechnology, University of Tokyo … Otani H, Udwary DW, Mouncey NJ. Comparative and pangenomic analysis of the genus Streptomyces. Sci Rep. 2022 …
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Ray Turner Completes Last Tour of Lab Duty at JGI
… as a typical monthly JGI All-Hands Meeting, after a couple of perfunctory items, the agenda went off the rails – according to plan but unbeknownst to Ray and … co-localization of JGI and KBase at the Integrative Genomics Building (IGB). Said Michael Brandt of Ray, “You …
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Benjamin Cole
… University of California, San Diego (PhD, 2011) Rensselaer Polytechnic … List of pubs available on NCBI … Implementation of the Index of Cell Identity as an R package … Selected Publications … Software …
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Yasuo Yoshikuni
… Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, strain engineering, and biosystems design … at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.  …
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Kjiersten Fagnan
… closely with staff to understand the data-intensive nature of JGI workloads. Dr. Fagnan was appointed CIO of the JGI in 2016, and in 2018 was hired to be the JGI’s … Methodologies workshops. In 2018, Dr. Fagnan was part of the Gordon Bell prizewinning team at the Supercomputing …
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Computationally Classifying Fungal Lifestyles
… genomes to classify gene families. The Science As a proof of concept, researchers developed an algorithm that “taught” … a computer how to classify 101 representative genomes of Dothideomycetes, the largest class of fungi, by … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Eelgrass Proves to Be Much Younger Than We Thought
… less than previously believed.  The Science Eelgrass, one of the most abundant plants in the ocean, originated in … assumed, due to the wide and varied geographic footprint of the plant, that eelgrass began colonizing the oceans  … the last 40,000 years. The Impact Eelgrass represents one of the largest carbon sinks in the ocean — occupying just …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… is not exclusively for Euryarchaeota. Atmospheric levels of methane, a potent greenhouse gas, regulate Earth’s … Euryarchaeota .  Finding Methane-Making Microbes with Metagenomics  By leveraging metagenomics to sample the entirety of a microbial community out …
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