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Tracking the Origins of Methane-Producing Microbes
… Mini-Metagenomics Approach Helps Identify Novel Archaeal Methane … Methane-producing archaea are estimated to produce 500 million tons of methane a year, which is over half the total … Biohub, and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user …
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How to Target a Microbial Needle within a Community Haystack
… A workflow for capturing the genetic make-up of specific uncultivated microbes from complex environmental samples. The Science A team led by researchers at … and then efficiently retrieve and characterize their genomes. The Impact Despite great strides in generating …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
… In honor of the JGI's 25th anniversary in 2022, we have … year, the JGI team reported the first closed and finished genome derived from an uncultured bacterial single cell – a …
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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and … to technical limitations and the sheer complexity of plant genomes. Now, with improvements to DNA Affinity Purification … robustness will enable researchers to propose multi-genome projects, opening new avenues for comparative regulatory …
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An Earth Month Look at Sustainability Efforts at the JGI
… Sustainable Berkeley Lab maintains a  calendar of Earth Month events throughout April. This year, a new group at the … now IGB-wide ZERO Waste Initiative began its most ambitious project yet: a special recycling program to recycle lab … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … challenges, characterizing viruses is a key step. For decades, though, many viruses have been somewhat invisible … Beginning in the early 2000s , these environmental metagenomes began to offer a window into viral existence. Along …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… For the first time, a team has comprehensively described host-virus dynamics in … In microbial mats, communities of microorganisms live among viruses that infect them. But what trends govern those … lysogeny, they can insinuate themselves inside the host’s genome, living quietly and replicating with their host …
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JGI Announces 2026 New Investigator Portfolio
… Pictured from left: [Top row]: Emily G. Aguirre, Shauna M. Bennett, Laura Bogar, Michael Borg, Rory … N. Zepernick.    Each year, the JGI solicits novel research projects from PIs who have not led any previously accepted … including metagenomics, metatranscriptomics and genome assembly to investigate microbial and plant …
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Nandita Nath
… Nandita is involved in developing new methods to improve genome … libraries from minimal DNA input without amplification. …
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JGIota: Looking Back at Sequencing for Soybeans
… The soybean is a crop that could boost biofuels and fertilize fields. So in 2010, the JGI helped publish the original genome sequence for the soybean, Glycine max. With a full … have been able to look into soybean’s strengths – along with a fungus that threatens this important crop. Hear …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… JGI-led team significantly expands the global diversity of large and … single drop of water could outnumber a small city’s population, the number of viruses in the same drop—the vast majority … archaea and eukaryotes, and they range in particle and genome size from small, to large and even giant. The genomes …
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Mike Sneddon
… Dr. Sneddon is the Advanced Analysis Group Lead in the Data Science and Informatics Department at the Joint Genome Institute. His team of engineers and scientists … Liu, O., Akiva, E., Eyles, T. H., Galm, U., Ganesh, S., Hendrix, S. … S., Pelikan, C., Scannell, D., Serber, Z., Shock, J., Sneddon, M., and Yang, X. Metagenomic library and natural product …
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