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Mining Metagenomes for Cas Proteins
… Cas14 proteins discovered from JGI’s IMG/M database and … possible by mining the datasets in the Integrated Microbial Genomes and Microbiomes (IMG/M) suite of tools managed by … by searching for Cas12d homologs across IMG/M’s assembled metagenomic data. It turned out that some of these were …
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Partnering with CalTeach – Training the Next Generation STEM Workforce
… Basepairs, A Vision for Integrative and  Collaborative Genome Science” – through early introduction to the …
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Sequence to Function: Applications and Analysis for the Future (SFA²F)
… and informal networking events. JGI will present both a genome center talk and a tech talk. Stop by the JGI booth to …
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JGIota: The Algae Nicknamed ‘Chlamy’
… works on this alga, how researchers managed to sequence its genome, and what it has to teach us about other organisms – …
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DAP-seq Drives Robust Mapping of Gene Regulation
… to technical limitations and the sheer complexity of plant genomes. Now, with improvements to DNA Affinity Purification … paper and Technical Implementation Lead at the DOE Joint Genome Institute (JGI), a DOE Office of Science User … happening in terms of where those binding sites are in the genome — those sequences are moving around, disappearing and …
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Exploring the Diversity of the American Prairie’s Switchgrass
… potential biofuel feedstock. But switchgrass has a complex genome and, as a species, encompasses dizzying diversity. …
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Extracting the Secrets of Secondary Metabolites
… Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due … CRAGE (Chassis-independent Recombinase-Assisted Genome Engineering) is a technique researchers can use to … users of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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A User-Centered Approach to Accessing JGI Data
… metadata criteria. Wilson said that the Data Portal and  Genome Portal will continue to run in parallel for now. Eventually, he added, the Genome Portal will be retired once the same features are … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Fungal Friends or Foes in Plant Roots
… plant host health. The Science Researchers compared the genomes of fungi that colonize Arabidopsis thaliana roots … populations around Europe. The JGI sequenced and annotated 41 fungal isolates from the collection. The team then … of the key community participants and enabling future metagenomics studies.   …
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Yasuo Yoshikuni
… production of biofuels and renewable chemicals, developing genome engineering tools for non-model organisms, modulating … efficient than glycolysis., Nature Chemical Biology , 2024 Dubinkina et al., A transcriptomic atlas of acute stress … Issatchenkia orientalis strains., Microbial Spectrum , 2024 Wu et al.Metabolic engineering of low-pH-tolerant …
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Mike Sneddon
… in the Data Science and Informatics Department at the Joint Genome Institute. His team of engineers and scientists … system. He previously led the NGS Software team and metagenomic data platform at Zymergen, a synthetic biology … D., Serber, Z., Shock, J., Sneddon, M., and Yang, X. Metagenomic library and natural product discovery platform. …
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Rex Malmstrom
… genomics pipeline that provides JGI users access to the genomes of uncultured microbes.  His group also handles the Stable Isotope Probing (SIP) Metagenomics pipeline  that reveals in situ functional … et al. 2024.  Spatial co-transcriptomics reveals discrete stages of the arbuscular mycorrhizal symbiosis. Nature Plants …
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