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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the … be engineered. “Piloting access to this emerging technology with JGI users will enable us to assess CRAGE’s impact, … as part of the Community Science Program (CSP)  Functional Genomics proposal call. …
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… ice in the Arctic has decreased by more than 30% in terms of quantity and thickness. Replacing older, thicker ice with younger, thinner ice means more fresh water — and less … surface where algae grow. Armed with a better understanding of the alga’s stress resistance and ability to adapt to …
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Zhong Wang
… new bioinformatics solutions to support JGI in adopting new genomics technologies, scaling up genomics analysis to … and enabling data-driven science. This is a group of computational biologists, bioinformaticians, computer … metagenome binning software … Education … Selected Publications … Software …
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Extracting the Secrets of Secondary Metabolites
… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due … payloads directly into diverse microbes. Combining CRAGE with CRISPR provides researchers with a powerful addition to …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… characteristics — creating many different ways of processing nitrogen. To boost crops more efficiently in … Korea as well as a faculty affiliate in the Environmental Genomics and Systems Biology Division of Lawrence Berkeley … National Laboratory (Berkeley Lab). He completed this work with collaborators at the University of Wisconsin-Madison as …
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Mindfully Moving JGI
JGI is in the process of shifting its operations from Walnut Creek to the heart of … 100 were silent. Twenty years after the JGI united the genomics expertise of three national labs in one long … years ago. For JGIers, the moving process began in 2017 with annual one-day cleanups. During those days, they were …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… on microbial communities than ever before — especially with the prospect of meta-analyses boosted by AI and Machine Learning — JGI … said. Informed by other community-driven standards from the Genomic Standards Consortium, Wilhelm and Simpson assembled …
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Phytozome: Tutorial Workshop from 2022 CROPS Conference @HudsonAlpha
… for Biotechnology. Phytozome is the Plant Comparative Genomics portal of the Department of Energy Joint Genome Institute, and facilitates accurate and insightful comparative genomics studies. …
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Danielle Goudeau
Danielle operates the single-cell genomics pipeline for JGI collaborators. This work combines … novel flow cytometry protocols for targeted recovery of specific microbes. …
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An Inside Look at How Plants and Mycorrhizal Fungi Cooperate
A new view into a symbiosis could offer benefits to address climate change: pulling … carbon into soil and boosting biofuel feedstocks with less fertilizer. For millions of years, underground … Berkeley National Laboratory, is committed to advancing genomics in support of DOE missions related to clean energy …
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An Inside Look at How Plants and Mycorrhizal Fungi Cooperate
A new view into a symbiosis could offer benefits to address climate change: pulling … carbon into soil and boosting biofuel feedstocks with less fertilizer. For millions of years, underground … Berkeley National Laboratory, is committed to advancing genomics in support of DOE missions related to clean energy …
Learn more
JGI at the AGU Fall Meeting
This year the AGU Fall Meeting, with the theme “Science is Society,” hosts sessions in New … Register for the meeting here. Here are some sessions of interest (all times in PST unless otherwise noted): … context for thousands of newly sampled microbial genomes from North American watersheds (Invited)” 4pm CST …
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