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2024 Progress Report
… for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … A record number of primary users — 2,475 — had active proposals with us, … processed 13,700 metabolomics samples With our users, 247 publications were published   …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… communities than ever before — especially with the prospect of meta-analyses boosted by AI and Machine Learning — JGI … communities. By pairing RNA or DNA sequencing with tracings of stable, heavy isotopes, SIP allows researchers to go … in microbial ecosystems. These communities harbor tens of thousands of different organisms who all consume …
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Extracting the Secrets of Secondary Metabolites
… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … effectiveness has historically been limited due to the lack of robust tools available for carrying CRISPR into … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … with the HudsonAlpha Institute for Biotechnology.   Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …
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JGI@25: From Life at the Extremes to Editing Genomes
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … nature was using it to do something important.” Related Publications:  A scoutRNA Is Required for Some Type V …
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Exploring Possibilities: 2022 JGI-UC Merced Interns
… And also specifically, it sparked my interest in bioformatics, so that’s what I’m gonna take with me to the … are a little bit stronger in computing, so I was kind of worried coming into the, the internship that maybe I didn’t have as good of skills as somebody else might have. But Robert, uh, Bob …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… A special issue of Synthetic Biology celebrates research enabled by the JGI … and synthesis work. This is where the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … more than 10 papers, including two Nature Plants publications, in five years, have come out of the …
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Mapping the Earth’s Hidden Fungal Kingdom
… Leveraging massive comparative genomics to decode millions of mystery genes and lay a future-ready foundation     Over … an estimated 2–6 million species — dwarfing the diversity of plants. To put this evolutionary timescale in … Earth's fungal kingdom. The manuscript reviews about 200 publications linking evolutionary history and innovations …
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Ray Turner Completes Last Tour of Lab Duty at JGI
… as a typical monthly JGI All-Hands Meeting, after a couple of perfunctory items, the agenda went off the rails – according to plan but unbeknownst to Ray and most of the rest of the 200-plus Zoom participants. While the … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Hiroshi Otani
… technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo PhD, Biotechnology, University of Tokyo … Udwary DW, Mouncey NJ. Comparative and pangenomic analysis of the genus Streptomyces. Sci Rep. 2022 Nov 7;12(1):18909. …
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Leo Baumgart
… his doctoral research in synthetic biology and microfluidics at the University of California, San Diego. As the Sequencing Technology … a method that enables high-throughput characterization of transcription factor binding sites and which has been … BS in Biochemistry and Cell Biology, University of California, San Diego PhD in Molecular Biology, …
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Katherine Louie
… efforts to expand the metabolomics capabilities and product offerings for JGI users.  Using cutting-edge mass … techniques, the platform delivers rich metabolite profiles from diverse biological and environmental samples in support of user science.  Capabilities offered by the platform are a …
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