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JGIota: The Algae Nicknamed ‘Chlamy’
… a tiny, single-celled alga – Chlamydomonas reinhardtii – that’s managed to have a big impact. UC Berkeley plant … works on this alga, how researchers managed to sequence its genome, and what it has to teach us about other organisms – like plants. [ …
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Learning to Look
… readers need to look for a number of distinguishing features. Several characters may be spotted with a striped … by scientists at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … are filamentous viruses with small, single-stranded DNA genomes and a unique chronic infection cycle. “We’re not …
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DAP-seq Drives Robust Mapping of Gene Regulation
… yield an unprecedented view of plant evolution and adaptation.    Understanding how genes are regulated is like … to technical limitations and the sheer complexity of plant genomes. Now, with improvements to DNA Affinity Purification … paper and Technical Implementation Lead at the DOE Joint Genome Institute (JGI), a DOE Office of Science User …
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Exploring the Diversity of the American Prairie’s Switchgrass
… A tall native plant of the North American prairie, switchgrass ( Panicum virgatum ) has long been a tantalizing potential biofuel feedstock. But switchgrass has a complex genome and, as a species, encompasses dizzying diversity. …
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Extracting the Secrets of Secondary Metabolites
… (Clustered Regularly Interspaced Short Palindromic Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due … CRAGE (Chassis-independent Recombinase-Assisted Genome Engineering) is a technique researchers can use to …
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A User-Centered Approach to Accessing JGI Data
… When the JGI Data Portal (https://data.jgi.doe.gov/) launched last year, … metadata criteria. Wilson said that the Data Portal and  Genome Portal will continue to run in parallel for now. Eventually, he added, the Genome Portal will be retired once the same features are …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… have made strides in improving and applying a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  … of DNA (up to 60 kb) in a single step, directly into the genome. “CRAGE is central to our ability to offer …
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Fungal Friends or Foes in Plant Roots
… Uncovering associations between plant roots and fungi that can help or harm … plant host health. The Science Researchers compared the genomes of fungi that colonize Arabidopsis thaliana roots with genomes from other plant-associated fungi. Their analysis … was funded by the U.S. Department of Energy (DOE) Joint Genome Institute, a DOE Office of Science User Facility, and …
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Yasuo Yoshikuni
… design for DOE-mission-relevant discovery and applications. This program has supported over 250 projects since it started. At the JGI, Dr. Yoshikuni also manages the Synthetic Biology … production of biofuels and renewable chemicals, developing genome engineering tools for non-model organisms, modulating …
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Mike Sneddon
… Dr. Sneddon is the Advanced Analysis Group Lead in the Data Science and Informatics Department at the Joint Genome Institute. His team of engineers and scientists … J., Sneddon, M., and Yang, X. Metagenomic library and natural product discovery platform. WO2021163637A1 , PCT …
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Rex Malmstrom
… is a Staff Scientist and leader of the Microscale Applications group. Before joining the JGI in 2010, he made the first ever measurements of in situ growth rates and carbon consumption of SAR11 bacteria, the most … genomics pipeline that provides JGI users access to the genomes of uncultured microbes.  His group also handles the …
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Simon Roux
… in 2017 to lead viral genomics research as part of the Metagenome Program. His responsibilities include the development of novel computational tools to identify virus sequences, the design of new … approaches to link viruses to their host(s), collaboration with JGI users for analyzing viral datasets, and the …
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