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Applying Viral Genomics Expertise to Understanding the Human Virome
… the stars in the Milky Way, viruses outnumber the microbes by at least another order of magnitude. For years, … and Simon Roux. Kyrpides is part of another project led by Owen White at the University of Maryland, Baltimore. Both … , 2021), geNomad , a tool for identifying mobile genetic elements ( Nature Biotechnology , 2024), and iPHoP , an …
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Triggering Morel Fruiting
A collaborative team led by Hao Tan from the Sichuan Academy of Agricultural Sciences … they influence geochemical cycling in forest ecosystems. By deciphering the fruiting-related decomposition mechanisms … catabolic enzymes for the decay apparatus. Consequently, it created a subtle flow of nitrogen from the soil towards the …
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The Power of One, Amplified
… the value of conducting large-scale single cell genomics by collecting nearly 500 single cells from a single low … specific sets of single cells harbored mobile genetic elements that were missed within paired metagenome assembled … genomes directly from environmental sequence data, by piecing each genome together from large mixtures of …
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FICUS
… beyond what each of these facilities could generate by itself.   Accepted projects must address or be otherwise … synthesis, metabolomics and analysis will be paid for by the Department of Energy’s funding of the JGI. There is … or outside the scope of the call.  Letters are reviewed by scientific staff of the participating User Facilities, as …
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Institutional User Agreements
… of sequencing data for synthesis. This agreement, required by the DOE for all work performed in its User Facilities, is … execute a 2024 version .  The recent updates were approved by the DOE to address the DNA Synthesis program. When fully … to a new commercial institution requires approval by all parties. … After your proposal is approved, the …
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Fields of Breeders’ Dreams: A Team Effort Toward Targeted Crop Improvements
As  reported January 27, 2021 in  Nature , the team led by researchers at the University of Texas (UT) at Austin, … —have expanded the network of common gardens and are exploring improvements to switchgrass through more targeted … a feedstock for biomass-based fuels was initially fostered by DOE’s Bioenergy Research Centers, which initiated the …
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Learning to Look
July 22, 2019, in  Nature Microbiology , a team led by scientists at the U.S. Department of Energy (DOE) Joint … sequence is most likely not an inovirus. But if these nearby genes are both short and novel, then that’s a very good … phages to help the bacterial host resist foreign genetic elements. In some cases, Roux and his colleagues found that …
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Mindfully Moving JGI
… from Walnut Creek to the heart of the Berkeley Lab campus. By Friday, October 18, the production sequencing labs in … (up to 120 sequencing machines at maximum) maintained by a workforce that numbered more than 100 at its peak, all …
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Doubling Down on Known Protein Families
… diversity is wilder than ever. Imagine researchers exploring a dark room with a flashlight, only able to … a novel approach to better understand microbial communities by looking at protein function within them. The work was led by a team of scientists at the U.S. Department of Energy …
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Pinning Down a Piece of Photosynthesis
By studying the structure and function of a cyanobacterial … no one’s ever had a structure of before,” said Crysten Blaby-Haas, a research scientist at the JGI and Molecular … heme molecule. In the protein structure Grosjean and Blaby-Haas studied, that sandwich has an additional outer layer …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
A group led by JGI scientists have made strides in improving and … often fail to express their BGC molecules in the lab. By engineering domesticated close relatives with the BGCs, … biology problems. For example, a group of JGI users led by Steven Hallam at the University of British Columbia, …
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A Redesign for Yeast’s Genome, Chromosome by Chromosome
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