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… included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … a team of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s … CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, but these …

… Genome annotations of two C. citriodora subspecies broaden … assembly of two Corymbia citriodora subspecies variegata genomes allowed researchers to study the conservation and … tissues of C. citriodora . From these samples, a total of 127 TPS loci were found, many of which had high sequence …

… was the last major crop without a reference quality genome and now crop researchers can work toward advancing … together a puzzle without necessarily knowing the final image. In contrast, assembling the sugarcane genome was more … partly enabled by the JGI’s Community Science Program; in 2018, a monoploid reference sequence of sugarcane …

… Microbiology column last year — and there’s more to come in 2020. Researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … in environmental genomics by writing for the column Genome Watch in  Nature Reviews Microbiology .  The latest …

… Grigoriev from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … demonstrating the common ancestry between fungi and animals. Olpidium attracted the attention of many mycologists with the two publications of the kingdom-wide, multi-gene phylogeny of …

… engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most living … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence … over 1.3 million publicly available bacterial and archaeal genome and contig sources.  The Impact Secondary metabolites …

… An improved genome assembly to support targeted tree breeding for the …   The Science Researchers report a new reference genome for eucalyptus in the July edition of the journal G3 … | Genetics , with significant advances compared to the 2014 Eucalyptus grandis reference genome that has been …

… products field as it relates to structure elucidation and genome mining, and how we might start to better connect those two things, because I think that’s ultimately what needs to happen if we’re really going to … Yeah, that’s right. We were postdocs together in the mid 2000s, I guess. You were working for Brad Moore. I was …

… results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for … Described in  ISME Communications , a method called Primary Template-Directed Amplification (PTA) yields a much … like plasmids, the picture is far from complete.  In 2021 , scientists at St. Jude Children’s Research Hospital …

… FY 2026 DOE Metrics Sequencing Quarter Total Bases (Trillions) … developments for improving microbial, metagenomic, or plant genome assemblies. [Download PDF] Q2 – Report on progress … the interpretation of microbial, metagenomic, or plant genomes. [Download PDF] End-of-year Goal – Develop one new …

… Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions of years … of the Earth’s atmosphere and regulating the global climate for life to flourish. For Guillaume Borrel and …