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Better Genome Editing for Bioenergy
… included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … a team of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s … a pool of sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized …
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Corymbia Genome Expands Terpene Synthesis Knowledge
… Genome annotations of two C. citriodora subspecies broaden … assembly of two Corymbia citriodora subspecies variegata genomes allowed researchers to study the conservation and … lot of rain.  Previous analysis of the E. grandis reference genome, an international effort by a team that included …
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Draft Genome Sequence of Bordetella sp. Strain FB-8, Isolated from a Former Uranium Mining Area in Germany
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A Complex Confection Decoded: Sugarcane Reference Genome
… was the last major crop without a reference quality genome and now crop researchers can work toward advancing … together a puzzle without necessarily knowing the final image. In contrast, assembling the sugarcane genome was more … to sort through in order to form a single cohesive image. An approximately nine billion base (Gigabase or Gb) …
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Natural Prodcast Episode 9: Roger Linington
… products field as it relates to structure elucidation and genome mining, and how we might start to better connect those two things, because I think that’s ultimately what needs to happen if we’re really going to … greatly benefit by knowing what’s already known. So you can imagine, if you have a particular sample, and you don’t have …
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JGI Scientists Pen Genome Watch Articles
… Researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … in environmental genomics by writing for the column Genome Watch in  Nature Reviews Microbiology .  The latest … consider regularly writing for the magazine’s column Genome Watch? The column appears in six issues of the …
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New and Improved: Eucalyptus Reference is Now Accessible
… An improved genome assembly to support targeted tree breeding for the …   The Science Researchers report a new reference genome for eucalyptus in the July edition of the journal G3 Genes | Genomes | Genetics , with significant advances compared to … Borevitz) conducted by the US Department of Energy Joint Genome Institute ( https://ror.org/04xm1d337 ), a DOE Office …
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Olpidium, The Key to the Origin of Terrestrial Fungi
… Grigoriev from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … demonstrating the common ancestry between fungi and animals. Olpidium attracted the attention of many mycologists with the two publications of the kingdom-wide, multi-gene phylogeny of …
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A Community Resource for Secondary Metabolite Researchers
… engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most living … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence … over 1.3 million publicly available bacterial and archaeal genome and contig sources.  The Impact Secondary metabolites …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for … Described in  ISME Communications , a method called Primary Template-Directed Amplification (PTA) yields a much … developed a new method of genome amplification called Primary Template-Directed Amplification (PTA) that yielded …
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DOE Metrics
… developments for improving microbial, metagenomic, or plant genome assemblies. [Download PDF] Q2 – Report on progress … the interpretation of microbial, metagenomic, or plant genomes. [Download PDF] End-of-year Goal – Develop one new …
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The Expanding Universe of Methane Metabolisms in Archaea
… Metagenome-assembled archaeal genomes provide new insights into … of the Earth’s atmosphere and regulating the global climate for life to flourish. For Guillaume Borrel and … the diversity of methane metabolisms is “vastly underestimated.” In the March 4, 2019, issue of Nature Microbiology …
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