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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… team has comprehensively described host-virus dynamics in a microbial mat. The Science In microbial mats, communities of microorganisms live among viruses that infect them. But … virus had been infecting the cell. The team assembled 130 genomes from their sample — a small proportion of the …
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From Competition to Cooperation
Tracking evolution of symbiotic lifestyles across multiple fungal lineages. The Science By comparing 135 fungal sequenced genomes, researchers were able to carry out a broader … of plant-host and mycorrhizal-fungal interactions. … The project was funded by the U.S. Department of Energy Joint …
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Computationally Classifying Fungal Lifestyles
Machine learning methods were applied on sequenced fungal genomes to classify gene families. The Science As a proof of concept, researchers developed an algorithm that … data generated in part through the 1000 Fungal Genomes Project, including 55 newly-sequenced species.  The Impact …
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Fungal Friends or Foes in Plant Roots
… plant host health. The Science Researchers compared the genomes of fungi that colonize Arabidopsis thaliana roots with … determine if these fungi act as friends or foes. The Impact Microbial communities comprised of fungi and bacteria can …
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Graduate Students Get Thesis Research Opportunity at the JGI
Twice a year, the DOE Office of Science Graduate Student Research (SCGSR) program … change and this is a remarkable opportunity to launch a pilot project and begin the work of understanding how … to an exceptional caliber of scientists.” For her project, “Microbial Community Structure and Methane Production in …
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A Collaboration to Improve Plant Genome Annotations Across Species
… which specializes in genome improvement for plants. As part of that partnership, the JGI and HudsonAlpha researchers led … were you working with? Avinash: In the initial planning phase, there were about 10 groups that came together to … Avinash:   JGI puts huge efforts into generating reference genomes for new species allowing it to fill gaps in the …
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Decoding Yellowstone’s Microbial Mats
… began oxygenating Earth over two billion years ago. A team of researchers set out to Yellowstone National Park to study how cyanobacteria are living, communally, in microbial mats. Along the way, they’ve encountered … new technologies, and made a few discoveries about the microbial mat denizens.  …
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FICUS Overview
… to more easily integrate the expertise and capabilities of multiple Department of Energy Office of Science National User Facilities into … and multidisciplinary nature of DOE mission science projects, this initiative aims to encourage innovative …
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Jeremy Schmutz
… human chromosomes 5, 16, and 19. Following the completion of the human genome project in 2003, he developed sequencing, assembly, and … eukaryotic organisms from simple yeasts to large vertebrate genomes.  For the past 13 years, Mr. Schmutz has directed …
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Uncovering Novel Genomes from Earth’s Microbiomes
Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … have uncovered genomes for just a small fraction of Earth’s microbial diversity. Because most microbes cannot be … called metagenome binning, we were able to reconstruct thousands of metagenome-assembled genomes (MAGs) directly …
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David Goodstein
… focused on building tools to facilitate expert curation of human gene models in support of JGI’s contributions to the Human Genome Project, he began developing larger comparative genomic … of interest and gene copy number variation across multiple genomes.  eLife 11, e78526. Li et al., 2021.  Plant …
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Learning to Look
… “Where’s Waldo?” readers need to look for a number of distinguishing features. Several characters may be … a computer could use to conduct a similar type of search in microbial and metagenomic databases. In this case, the … are filamentous viruses with small, single-stranded DNA genomes and a unique chronic infection cycle. “We’re not …
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