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… To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone Health) and Leslie Mitchell (Neochromosome) have worked … the goal is to create an entirely human-generated yeast genome. …

… The JGI’s Genomes OnLine Database celebrates 25 years as a vital resource for … the growth of different entities,  further outlined in the journal  Nucleic Acids Research in November 2022.  One of … U.S. Department of Energy Joint Genome Institute (https://ror.org/04xm1d337), a DOE Office …

… JGI by identifying the actual molecules present in an environment that influence system behavior.  Through this identification, metabolomics enables functional genome annotation, improves understanding of the role small … Find more details on the instrumentation we use and our methodology for …

… Congratulations to Jane Grimwood, who has been appointed the … City. Grimwood is also co-director of the HudsonAlpha Genome Sequencing Center. Grimwood heads the Library … soon after the JGI was established to work on the Human Genome Project in 1997. She was a group lead at Stanford …

…   The Joint Genome Institute's Biodesign Platform capabilities support researchers exploring how to convert sequence into functional assessments. This is done by synthesizing genes, … of tools to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods …

… Registration has closed.  The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is offering a five-day workshop on … designed to familiarize users with the Integrated Microbial Genomes & Microbiomes (IMG/M) data and workflows for …

… in 2011, JGI-supported researchers published a paper in the journal Science . It detailed how they’d used metagenomics … State University campuses for biotechnology education as part of a course-based undergraduate resource … Hess, also the chair of the JGI User Executive Committee, on how that study went from the lab to the classroom. …

… at the University of Texas (UT) at Austin, the HudsonAlpha Institute for Biotechnology (HudsonAlpha), and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … This means it contains more than two copies of the genome , which can have pronounced ecological and …

… prokaryotes. The Science Most organisms use oxygen to convert food into energy. However, in environments with … including the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … browser that allows other researchers to study the genomes and predict the metabolic abilities of these …

… technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput … included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … a team of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s …

… make-up of specific uncultivated microbes from complex environmental samples. The Science A team led by researchers at … and then efficiently retrieve and characterize their genomes. The Impact Despite great strides in generating … DNA could be sequenced. Their protocol,  detailed in the journal  Microbiome , combines multiple techniques and was …

… over the last  25-plus years since the JGI’s inception, making it possible for researchers to get a close look … to enable large-scale analysis. The story of a massive metagenome assembly for a time-series experiment from the … microbes at Lake Mendota, which borders the University of Wisconsin-Madison, for over 20 years in order to better …