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Better Genome Editing for Bioenergy
… technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput … included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … a team of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s …
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JGI@25: Using Team Science to Build Communities Around Data
In honor of the JGI's 25th anniversary in 2022, we have … (Graphic: Neil Byers) The JGI launched the 1000 Fungal Genomes (1KFG) Project through a 2012 Community Science … State University led the effort to sequence 1000 fungal genomes to create two reference genomes for all fungi …
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JGIota: Looking Back at How Cow Rumen Samples Landed on a Syllabus
… in 2011, JGI-supported researchers published a paper in the journal Science . It detailed how they’d used metagenomics … State University campuses for biotechnology education as part of a course-based undergraduate resource … Hess, also the chair of the JGI User Executive Committee, on how that study went from the lab to the classroom. …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
In honor of the JGI's 25th anniversary in 2022, we have … help solve energy and environmental challenges.   The Human Genome Project began in 1990 when the U.S. Department of … studying Chromosome 5, which contains about 6% of the human genome . They discovered genes linked to conditions such as …
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Annual Genomics of Energy & Environment Meeting
Thank you for joining us at the 2024 DOE Joint Genome Institute (JGI) Annual Genomics of Energy & Environment Meeting! The JGI convenes this annual gathering of leaders from diverse …
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A Community Resource for Secondary Metabolite Researchers
The Secondary Metabolism Collaboratory encourages user engagement. … (BGCs.) As reported in the recent Database issue of the journal Nucleic Acids Research , the Secondary Metabolism … over 1.3 million publicly available bacterial and archaeal genome and contig sources.  The Impact Secondary metabolites …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c … of DNA (up to 60 kb) in a single step, directly into the genome. “CRAGE is central to our ability to offer …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… hitchhikers. These organisms are abundant and yet exceptionally small, with mini genomes to match. As a result, they cannot process all of … microorganisms had a close relationship. Then, using metagenomes and metatranscriptomes generated by the U.S. …
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The Expanding Universe of Methane Metabolisms in Archaea
Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. … Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea …
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Igor Grigoriev
Dr. Grigoriev joined the DOE Joint Genome Institute in 2003, following his postdoctoral … Institute, a Senior Scientist at Lawrence Berkeley National Laboratory, and an Adjunct Professor of Plant and … 2012 Editorial Board: BMC Fungal Biology and Biotechnology, Journal of Fungi, AIM Microbiology … Fungal & Algal Science …
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John Vogel
Dr. Vogel joined JGI in 2014 to establish a plant functional genomics program. Prior to this, he served as a … techniques) and utilizing these resources to understand genome organization and regulation, abiotic stress … : Deep Sequencing of Highly Diverse Inbred Lines 2014 Plant Journal 79: 361–374 DOI: 10.1111/tpj.12569 Hsia, et. al. …
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New Research Sheds Light on Diversity in the Deep Sea
… array of microorganisms adapted to living in extreme conditions. At these vents, and underwater volcanoes,  … from Portland State University and the University of Wisconsin-Madison collected 40 samples from five oceanic … Scientists with the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility at …
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