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… of Natural Prodcast. A little bit of a bonus episode, since I’m off schedule, but this is an important one that … is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … and where we are today. After that, we have lots of great conversations that we’ve already recorded with some …

… of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, … Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… Overview The JGI provides sequencing, synthesis, and targeted metabolomics support for DOE-BER funded awards, including awards funded through  BER Funding Opportunity … capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA …

… Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it going?  DAN: Good. How are you?  MARCY: Am fine. I live in a … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility located at … The JGI consists of 225 researchers and support staff in the Integrative Genomics Building in Berkeley, … The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a high-throughput AI-centric …

… Biology is currently experiencing a revolution brought on by rapid developments in genomics and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational technology … The research efforts of the group have concentrated in demonstrating the power of data science in tackling grand …

… UDWARY: It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for … at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …

… Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s … about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …

… back to a new session of Natural Prodcast. I’ve got two things I wanted to tell you about in this introduction. First … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, …

… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, Biodesign and pathway … sequencing products below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the standard analysis is … in length, cloned into vector of choice Glycerol stock of sequence verified clone 102/NA DNA Synthesis Constructs …