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… email once the samples are received and checked into our freezer.  Your project manager will keep you updated as your … pipelines.  You will receive automated emails as raw sequence data becomes available, and as analysis is …

… more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … and store. They’re easy to grow up, easy to throw in a freezer. Most of the successful genome mining has been in … for us– what organisms people use for genome mining, why it’s called genome mining, how the biosynthetic gene …

… enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh … Grad students need calories from somewhere. If it’s not free pizza at the seminar, then it’s going to have to be the …

… we can foster a respectful, collaborative environment free of harassment. To uphold Berkeley Lab’s enduring … Exercise tolerance for diverse ideas and a commitment to free inquiry based on evidence and criticism; Respect the …

… for everyone. We are dedicated to providing a harassment-free environment for everyone. We do not tolerate the … form. Engage respectfully on diverse ideas and a commit to free inquiry based on evidence and criticism. …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a … And I think in my opinion– and people are definitely free to disagree with me. But as the government scientist …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … able to produce chemistry that deals with reactive oxygen species and so potentially could go down that route.  DAN: … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on a regular basis, in accordance with …

And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … So you can knock out an acyltransferase and then use a free hydroxyl group and do some chemistry and get around …

… culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or whatever. And so I was … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? … is there’s this amazing resource that can be provided for free to scientists to use. They are actively looking for …

… aflatoxin being a secondary metabolite from an Aspergillus species that is pretty toxic – can cause liver cancer and … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk …