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… come, though, too when you start talking about going after single gene clusters. BRIAN BACHMANN: That’s right. JACKIE … mammalian systems. But it allows us to assay on a single cell level against cell lines and against primary cells … by chemical synthesis and make analogs in combination of mutagenesis and direct evolution. Yeah. DAN UDWARY: So it’s …

… types) (Nature Communications 2017, Science 2018, Molecular Cell 2019) and massive reconstruction of genomes from … Unraveling the functional dark matter through global metagenomics. Nature . 622(7983):594-602. Camargo AP. et al. … Bowers RM, et al. (2017) Minimum information about a single amplified genome (MISAG) and a metagenome-assembled …

… quantities of DNA derived from individual environmental cells. The proof of principle study built off earlier … and finished genome derived from an uncultured bacterial single cell – a symbiont of the green sharpshooter. In 2012, … of the tree of life. Used in tandem over the years, metagenomics and single cell genomics have afforded JGI users …

Accessing Resources at Multiple DOE User Facilities with a Single Proposal describes the resources available from the …

… community as a user facility pioneering functional genomics to solve the most relevant bioenergy and … the Letter of Intent; rather proposals are submitted in a single step. … The researcher then submits a proposal for …

The Metagenome Program uses advanced sequencing technologies to … and characterizing microbial diversity, work in the Metagenome Program uses several experimental approaches to … such as quantitative stable isotope probing (qSIP)-metagenomics and metatranscriptomics, to metagenomics and …

Celebrating 25 years of genomics research 2022 marked the JGI’s 25th anniversary. We … to advancing the frontiers of environmental and energy genomics. The two-story mural at the Integrative Genomics Building was painted by Berkeley-based artist Nigel …

The CSP Functional Genomics call is to enable users to perform state-of-the-art functional genomics research and to help them translate genomic …

… required documentation here .  … You can request a JGI Single Sign On account at https://signon.jgi.doe.gov . This … IMG (citation: https://doi.org/10.1093/nar/gkaa939 ) Metagenomes and Single Cells: IMG/M   (citation: …

… a great opportunity to learn more about JGI, hear some excellent talk from our users and from other invited guests, … in an obvious way. NIGEL MOUNCEY: We did a little bit of metagenome screening work and did find related clusters. But … and the stabilized isotope probing work that we’re doing, single cell work we’re doing. And using these together along …

… that might need special technology for DNA sequencing, genomics, metabolomics, and synthetic biology, that maybe … great conversations that we’ve already recorded with some excellent scientists, and that’s probably how we’ll continue … tree and became incorporated. And because it had some advantage to the tree – it almost certainly, you know, prevents …

… the Eloe-Fadrosh group focuses on using genome-resolved metagenomic approaches to identify and characterize genomic … computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … communities and ecosystem function.  The Environmental Genomics group also hosts the Viral Genomics group . …